Gene Symbol |
PTDSS1
|
Entrez Gene |
509819
|
Alt Symbol |
PSS-1
|
Species |
Bovine
|
Gene Type |
protein-coding
|
Description |
phosphatidylserine synthase 1
|
Other Description |
ptdSer synthase 1|serine-exchange enzyme I
|
Swissprots |
F1MKI4 Q2KHY9
|
Accessions |
DAA22521 Q2KHY9 BC112833 AAI12834 NM_001046040 NP_001039505
|
Function |
Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine (By similarity). {ECO:0000250}.
|
Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Highly enriched in the mitochondria-associated membrane (MAM). {ECO:0000250}.
|
Top Pathways |
Glycerophospholipid metabolism
|