TPMT

Gene Symbol TPMT
Entrez Gene 7172
Alt Symbol -
Species Human
Gene Type protein-coding
Description thiopurine S-methyltransferase
Other Description S-adenosyl-L-methionine:thiopurine S-methyltransferase
Swissprots Q9UBE6 O15515 P51580 O15423 O15548 Q9UBT8 O14806 O15426 O15424 O15425 Q9UE62 Q5VUK6 O43213
Accessions AAB71625 AAB71626 AAB71627 AAB71628 AAB71629 AAB71630 AAB71631 AAB71632 AAB71633 AAB71634 AAB71635 AAB71636 AAC32289 AAC50368 AAC51865 BAA97037 EAW55393 EAW55394 EAW55395 EAW55396 EAW55397 EAW55398 EAW55399 P51580 AA746081 AA825975 AF021876 AAB80746 AF021877 AAB80747 AK310420 BC005339 AAH05339 BC009596 AAH09596 BI598325 DB481604 HQ448729 ADQ33207 HY252883 HY300307 S62904 AAB27277 U12387 AAC50130 XM_011514839 XP_011513141 XM_011514840 XP_011513142 NM_000367 NP_000358
Function Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine. {ECO:0000269|PubMed:18484748}.
Subcellular Location Cytoplasm.
Top Pathways Drug metabolism - other enzymes

TPMT (E-8) - sc-374154 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TPMT (E-8): sc-374154. Western blot analysis of TPMT expression in K-562 (A) and HEL 92.1.7 (B) whole cell lysates.

TPMT (H-78) - sc-135249 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TPMT (H-78): sc-135249. Western blot analysis of TPMT expression in human bone marrow tissue extract.

TPMT (K-18) - sc-47506 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TPMT (K-18): sc-47506. Western blot analysis of TPMT expression in K-562 (A), HEL 92.1.7 (B) and TF-1 (C) whole cell lysates.

TPMT (N-13) - sc-47507 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-TPMT antibody - ab180810 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human esophagus tissue labelling TPMT with ab180810 at 1/100. Magnification: 200x.

Anti-TPMT antibody - ab58340 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
TPMT antibody (ab58340) used in immunofluorescence at 10ug/ml on HeLa cells.

Anti-TPMT antibody - ab191287 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TPMT antibody (ab191287) at 2 µg/mlLane 1 : EC109 whole cell lysateLane 2 : 293T whole cell lysateSecondaryGoat polyclonal to Rabbit IgG antibody at 1/15000 dilution

Anti-TPMT antibody - ab58343 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab58343 TPMT antibody at 1ug/ml.

Anti-TPMT antibody [AT2E7] - ab122984 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AT2E7
Anti-TPMT antibody [AT2E7] (ab122984) at 1/1000 dilution + Hep3B lysate at 40 µgSecondarygoat anti-mouse secondary antibody conjugated to HRPdeveloped using the ECL technique

Anti-TPMT antibody [EPR10820(B)] - ab155284 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10820(B)
All lanes : Anti-TPMT antibody [EPR10820(B)] (ab155284) at 1/1000 dilutionLane 1 : K562 cell lysateLane 2 : TF1 cell lysateLane 3 : Jurkat cell lysateLane 4 : HepG2 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-TPMT antibody [EPR10821(B)] - ab166909 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10821(B)
All lanes : Anti-TPMT antibody [EPR10821(B)] (ab166909) at 1/1000 dilutionLane 1 : K562 cell lysateLane 2 : HepG2 cell lysateLane 3 : Jurkat cell lysateLane 4 : TF-1 cell lysateLysates/proteins at 10 µg per lane.

Anti-TPMT Antibody (clone 4C1) - LS-C115096 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4C1
IHC of paraffin-embedded Carcinoma of liver tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).

Anti-TPMT Antibody - LS-C331205 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human esophageal cancer using TPMT antibody at dilution of 1:100 (200x lens).

Anti-TPMT Antibody (clone 2A2) - LS-C115018 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A2
IHC of paraffin-embedded Adenocarcinoma of ovary tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).

Anti-TPMT Antibody (N-Terminus) - LS-C92740 from LifeSpan Bioscience

Prices $295.00
Sizes 40 µg
Host Rabbit
Clonality Polyclonal

Anti-TPMT Antibody (aa200-250) - LS-C92741 from LifeSpan Bioscience

Prices $295.00
Sizes 40 µg
Host Rabbit
Clonality Polyclonal

Anti-TPMT Antibody (Biotin) - LS-C183350 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TPMT Antibody (FITC) - LS-C183351 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TPMT Antibody (HRP) - LS-C183352 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TPMT Antibody - LS-C190041 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TPMT Antibody (aa152-201) - LS-C146543 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TPMT antibody LS-C146543 Western blot of 3 Cell lysate. Antibody concentration 1 ug/ml.

Anti-TPMT Antibody (clone AT2E7) - LS-C175796 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AT2E7
Western Blot: The cell lysates (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human TPMT antibody (1:1,000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Anti-TPMT Antibody (aa200-250) - LS-C203047 from LifeSpan Bioscience

Prices $245.00
Sizes 40 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant human TPMT protein using 1 ug/ml Rabbit Anti-TPMT Polyclonal Antibody. The signal was developed with IRDye 800 Conjugated Goat Anti-Rabbit IgG.

Anti-TPMT Antibody - LS-C192514 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of TPMT pAb in extracts from K562 cells and mouse liver, kidney tissues.

Anti-TPMT Antibody (N-Terminus) - LS-C203085 from LifeSpan Bioscience

Prices $245.00
Sizes 40 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant human TPMT protein using 1 ug/ml Rabbit Anti-TPMT Polyclonal Antibody. The signal was developed with IRDye 800 Conjugated Goat Anti-Rabbit IgG.
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