Gene Symbol |
Hyou1
|
Entrez Gene |
192235
|
Alt Symbol |
Cab140, Orp150
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
hypoxia up-regulated 1
|
Other Description |
150 kDa oxygen-regulated protein|ORP-150|hypoxia up-regulated protein 1|oxygen regulated protein (150kD)
|
Swissprots |
Q63617
|
Accessions |
EDL95301 EDL95302 Q63617 BC065310 AAH65310 CB691248 U41853 AAB05672 XM_006242884 XP_006242946 XM_006242885 XP_006242947 XM_008766143 XP_008764365 NM_001034028 NP_001029200 NM_138867 NP_620222
|
Function |
Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding (By similarity). {ECO:0000250}.
|
Subcellular Location |
Endoplasmic reticulum lumen.
|
Tissue Specificity |
Selectively expressed by cultured astrocytes but not endothelial cells, microglia or neurons.
|
Top Pathways |
Protein processing in endoplasmic reticulum
|