| Gene Symbol |
RELT
|
| Entrez Gene |
84957
|
| Alt Symbol |
TNFRSF19L, TRLT
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RELT tumor necrosis factor receptor
|
| Other Description |
receptor expressed in lymphoid tissues|tumor necrosis factor receptor superfamily member 19L
|
| Swissprots |
Q86V34 Q969Z4 Q96JU1 Q9BUX7
|
| Accessions |
EAW74892 EAW74893 EAW74894 EAW74895 EAW74896 EAW74897 EAW74898 Q969Z4 AF319553 AAK77356 AK027899 BAB55441 AK057036 BAG51848 AK074128 BAB84954 AK310103 BC001812 BC017279 AAH17279 BC051810 AAH51810 DQ892618 ABM83544 DQ895858 ABM86784 XM_005274356 XP_005274413 XM_006718714 XP_006718777 XM_011545305 XP_011543607 XR_950080 NM_032871 NP_116260 NM_152222 NP_689408
|
| Function |
Mediates activation of NF-kappa-B. May play a role in T- cell activation.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:16389068}; Single-pass type I membrane protein {ECO:0000269|PubMed:16389068}. Cytoplasm {ECO:0000269|PubMed:16389068}.
|
| Tissue Specificity |
Highest levels are in spleen, lymph node, thymus, peripheral blood leukocytes, bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in brain, kidney and pancreas. {ECO:0000269|PubMed:16389068}.
|
| Top Pathways |
Cytokine-cytokine receptor interaction
|
![Western Blot: RELT Overexpression Lysate (Adult Normal) [NBL1-15278] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RELT.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8780_RELT%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15278-img0002.jpg)
![Western Blot: RELT Overexpression Lysate (Adult Normal) [NBP2-09936] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RELT.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4628_RELT%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-09936-img0001.jpg)