Gene Symbol | PABPC3 |
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Entrez Gene | 5042 |
Alt Symbol | PABP3, PABPL3, tPABP |
Species | Human |
Gene Type | protein-coding |
Description | poly(A) binding protein, cytoplasmic 3 |
Other Description | PABP-3|poly(A)-binding protein 3|poly(A)-binding protein-like 3|polyadenylate-binding protein 3|testis PABP|testis-specific poly(A)-binding protein (PABP)|testis-specific poly(A)-binding protein 3 |
Swissprots | Q9H086 Q8NHV0 Q9H361 |
Accessions | AAK52448 ABB92425 EAX08360 Q9H361 AA954581 AF132026 AAG38953 AK313336 BAG36140 AL136900 CAB66834 BC027617 AAH27617 BC045608 AAH45608 BG718483 DQ892103 ABM83029 DQ895297 ABM86223 NM_030979 NP_112241 |
Function | Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Binds poly(A) with a slightly lower affinity as compared to PABPC1. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Testis specific. {ECO:0000269|PubMed:11328870}. |
Top Pathways | RNA degradation, RNA transport, mRNA surveillance pathway |
PABPC3 CRISPR/Cas9 KO Plasmid (h) - sc-410923 from Santa Cruz Biotechnology
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PABPC3 HDR Plasmid (h) - sc-410923-HDR from Santa Cruz Biotechnology
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PABPC3 Double Nickase Plasmid (h) - sc-410923-NIC from Santa Cruz Biotechnology
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PABPC3 Double Nickase Plasmid (h2) - sc-410923-NIC-2 from Santa Cruz Biotechnology
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PABPC3 CRISPR Activation Plasmid (h) - sc-410923-ACT from Santa Cruz Biotechnology
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PABPC3 CRISPR Activation Plasmid (h2) - sc-410923-ACT-2 from Santa Cruz Biotechnology
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PABPC3 Lentiviral Activation Particles (h) - sc-410923-LAC from Santa Cruz Biotechnology
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PABPC3 Lentiviral Activation Particles (h2) - sc-410923-LAC-2 from Santa Cruz Biotechnology
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PABPC3 siRNA (h) - sc-106346 from Santa Cruz Biotechnology
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PABPC3 shRNA Plasmid (h) - sc-106346-SH from Santa Cruz Biotechnology
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PABPC3 shRNA (h) Lentiviral Particles - sc-106346-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU113851 from Sigma-Aldrich
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MISSION® esiRNA - EHU127041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16251 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16251 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03978 from Sigma-Aldrich
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PABPC3 siRNA (Human) - CRH3350 from Cohesion Biosciences
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PABPC3 RNAi - H00005042-R01 from Novus Biologicals
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shRNA set against Human PABPC3 (NM_030979.2) - SHH369772 from Creative biogene
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shRNA set against Human PABPC3(NM_030979.2) - SHR077106 from Creative biogene
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Human PABPC3 siRNA - orb263852 from Biorbyt
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PABPC3 shRNA Plasmid (Human) - CHH3350 from Cohesion Biosciences
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PABPC3 miRNA 3'UTR clone - MiUTR1H-07455 from Creative biogene
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