| Gene Symbol |
TMC6
|
| Entrez Gene |
11322
|
| Alt Symbol |
EV1, EVER1, EVIN1, LAK-4P
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane channel-like 6
|
| Other Description |
epidermodysplasia verruciformis 1|epidermodysplasia verruciformis protein 1|expressed in activated T/LAK lymphocytes|protein LAK-4|transmembrane channel-like protein 6
|
| Swissprots |
Q8IUI7 Q7Z403 Q8TEQ7 Q9HAG5 O43284 Q45VJ2 Q8IU98 Q8IWU8
|
| Accessions |
EAW89487 EAW89488 EAW89489 EAW89490 EAW89491 EAW89492 EAW89493 Q7Z403 AB002405 BAA24179 AK021738 BAB13884 AK074065 BAB84891 AK096076 BAG53207 AK303165 BAG64265 AK303584 BAG64602 AK310734 AY057379 AAL25836 AY099356 AAM44452 AY099357 AAM44453 AY236496 AAP69874 BC007766 AAH07766 BC018346 AAH18346 BC023597 AAH23597 BC035648 AAH35648 DQ104440 AAZ20186 DQ892316 ABM83242 DQ895518 ABM86444 XM_005256995 XP_005257052 XM_005256996 XP_005257053 XM_005256997 XP_005257054 XM_005256998 XP_005257055 XM_011524255 XP_011522557 XM_011524256 XP_011522558 XM_011524257 XP_011522559 XM_011524258 XP_011522560 XR_243632 NM_001127198 NP_001120670 NM_007267 NP_009198
|
| Function |
Probable ion channel. {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:12426567}; Multi-pass membrane protein {ECO:0000269|PubMed:12426567}.
|
| Tissue Specificity |
Expressed in placenta, prostate, testis, activated T-lymphocytes and lymphokine-activated killer (LAK) lymphocytes. {ECO:0000269|PubMed:12906855, ECO:0000269|Ref.3}.
|
![Western Blot: TMC6 Overexpression Lysate (Adult Normal) [NBP2-07512] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TMC6.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8566_TMC6%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07512-img0001.jpg)
![Western Blot: TMC6 Overexpression Lysate (Adult Normal) [NBP2-09429] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TMC6.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10669_TMC6%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-09429-img0001.jpg)