Gene Symbol |
Btla
|
Entrez Gene |
208154
|
Alt Symbol |
A630002H24
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
B and T lymphocyte associated
|
Other Description |
B and T lymphocyte attenuator|B- and T-lymphocyte attenuator|B- and T-lymphocyte-associated protein
|
Swissprots |
Q7TSA3
|
Accessions |
EDK98062 EDK98063 Q7TSA3 AK041334 BAC30910 AY293285 AAP44002 BB123968 BC108963 AAI08964 BC108964 AAI08965 XM_006521907 XP_006521970 XM_006521908 XP_006521971 XM_006521909 XP_006521972 NM_001037719 NP_001032808 NM_177584 NP_808252
|
Function |
Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response.
|
Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
Tissue Specificity |
Expressed in splenic T- and B-cells as well as lymph node tissues but very weakly in somatic tissues. Also expressed in macrophages, NK cells and dendritic cells. A polymorphic tissue distribution between several strains is seen. {ECO:0000269|PubMed:12796776, ECO:0000269|PubMed:15749870}.
|