| Gene Symbol |
LST1
|
| Entrez Gene |
7940
|
| Alt Symbol |
B144, D6S49E, LST-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
leukocyte specific transcript 1
|
| Other Description |
leukocyte-specific transcript 1 protein|lymphocyte antigen 117
|
| Swissprots |
O00452 B0S8E1 O00454 Q5STA6 Q9UJS1 Q5SP24 Q9UJR6 Q13669 Q5HYS9 Q5STW6 Q9UJR8 Q2HNT3 Q9UJR7 O00453 B0S8E0 Q5STA5 B0S8E5 Q5STA7 Q5STA8 Q9UJR5
|
| Accessions |
AAB57724 AAD18090 BAB63394 EAX03427 EAX03428 EAX03429 EAX03430 EAX03431 EAX03432 EAX03433 EAX03434 EAX03435 EAX03436 EAX03437 EAX03438 O00453 AF000424 AAB86998 AF000425 AAB86999 AF000426 AAB87000 AI091696 AJ705986 AV711621 AV715235 AW925228 AY852265 AAX45331 AY852266 AAX45332 BC103855 AAI03856 BC103856 AAI03857 BI838080 BX647293 CD742958 DQ099382 AAZ13758 Y18486 CAB59904 Y18487 CAB59905 Y18488 CAB60038 Y18489 CAB59906 Y18490 CAB59903 XM_006715206 XP_006715269 XM_006715209 XP_006715272 XM_006715210 XP_006715273 XM_006725044 XP_006725107 XM_006725047 XP_006725110 XM_006725048 XP_006725111 XM_006725522 XP_006725585 XM_006725525 XP_006725588 XM_006725526 XP_006725589 XM_006725741 XP_006725804 XM_006725744 XP_006725807 XM_006725745 XP_006725808 XM_006725848 XP_006725911 XM_006725851 XP_006725914 XM_006725852 XP_006725915 XM_006725937 XP_006726000 XM_006725940 XP_006726003 XM_006725941 XP_006726004 XM_006726038 XP_006726101 XM_006726041 XP_006726104 XM_006726042 XP_006726105 XM_006726126 XP_006726189 XM_006726129 XP_006726192 XM_006726130 XP_006726193 XM_011514914 XP_011513216 XM_011546322 XP_011544624 XM_011547315 XP_011545617 XM_011547717 XP_011546019 XM_011547934 XP_011546236 XM_011548103 XP_011546405 XM_011548302 XP_011546604 XM_011548487 XP_011546789 NM_001166538 NP_001160010 NM_007161 NP_009092 NM_205837 NP_995309 NM_205838 NP_995310 NM_205839 NP_995311 NM_205840 NP_995312 NR_029461 NR_029462
|
| Function |
Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation. {ECO:0000269|PubMed:10706707, ECO:0000269|PubMed:11478849}.
|
| Subcellular Location |
Membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Endomembrane system; Single-pass membrane protein. Note=Also detected in a perinuclear region corresponding to the localization of the Golgi apparatus and throughout the cytoplasm.
|
| Tissue Specificity |
Expressed in lung, tonsil, thymus, placenta, kidney, fetal spleen, fetal liver and brain. {ECO:0000269|PubMed:7590964, ECO:0000269|PubMed:9367684}.
|