Gene Symbol | RALGPS1 |
---|---|
Entrez Gene | 9649 |
Alt Symbol | RALGEF2, RALGPS1A |
Species | Human |
Gene Type | protein-coding |
Description | Ral GEF with PH domain and SH3 binding motif 1 |
Other Description | Ral guanine nucleotide exchange factor RalGPS1A|RalGEF 2|ral GEF with PH domain and SH3-binding motif 1|ral guanine nucleotide exchange factor 2|ralA exchange factor RalGPS1|ras-specific guanine nucleotide-releasing factor RalGPS1 |
Swissprots | Q5JUG5 E9PBQ5 Q5JS13 B4DR86 Q9NZ16 O15059 Q5JT60 Q5JT65 Q8N4S6 Q8N5H4 Q8WUV7 |
Accessions | EAW87645 EAW87646 EAW87647 EAW87648 Q5JS13 AB002349 BAA20808 AF221098 AAF65253 AK299149 BAG61198 BC019329 AAH19329 BC032372 AAH32372 BC033708 AAH33708 BX648170 BY797926 CB162049 CN266562 DB332662 DB521440 DR001330 XM_006717327 XP_006717390 XM_006717328 XP_006717391 XM_011519225 XP_011517527 XM_011519226 XP_011517528 XM_011519227 XP_011517529 XM_011519228 XP_011517530 XM_011519229 XP_011517531 XM_011519230 XP_011517532 XM_011519231 XP_011517533 XM_011519232 XP_011517534 XM_011519233 XP_011517535 XM_011519234 XP_011517536 XM_011519235 XP_011517537 XM_011519236 XP_011517538 XM_011519237 XP_011517539 XM_011519238 XP_011517540 XM_011519239 XP_011517541 XM_011519240 XP_011517542 XR_929879 NM_001190728 NP_001177657 NM_001190729 NP_001177658 NM_001190730 NP_001177659 NM_014636 NP_055451 |
Function | Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity). Guanine nucleotide exchange factor for. {ECO:0000250, ECO:0000269|PubMed:10747847, ECO:0000269|PubMed:10889189}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:10889189}. Cell membrane {ECO:0000269|PubMed:10889189}. Note=Associates with membranes through the PH domain. |
Tissue Specificity | Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, pancreas, skeletal muscle, small intestine and thymus. {ECO:0000269|PubMed:10747847, ECO:0000269|PubMed:10889189}. |
Ral GPS1 CRISPR/Cas9 KO Plasmid (h) - sc-411305 from Santa Cruz Biotechnology
|
||||||||
Ral GPS1 HDR Plasmid (h) - sc-411305-HDR from Santa Cruz Biotechnology
|
||||||||
Ral GPS1 Double Nickase Plasmid (h) - sc-411305-NIC from Santa Cruz Biotechnology
|
||||||||
Ral GPS1 Double Nickase Plasmid (h2) - sc-411305-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Ral GPS1 CRISPR Activation Plasmid (h) - sc-411305-ACT from Santa Cruz Biotechnology
|
||||||||
Ral GPS1 CRISPR Activation Plasmid (h2) - sc-411305-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Ral GPS1 Lentiviral Activation Particles (h) - sc-411305-LAC from Santa Cruz Biotechnology
|
||||||||
Ral GPS1 Lentiviral Activation Particles (h2) - sc-411305-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Ral GPS1 siRNA (h) - sc-92962 from Santa Cruz Biotechnology
|
||||||||
Ral GPS1 shRNA Plasmid (h) - sc-92962-SH from Santa Cruz Biotechnology
|
||||||||
Ral GPS1 shRNA (h) Lentiviral Particles - sc-92962-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU139861 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN17928 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17928 from Sigma-Aldrich
|
||||||||
RALGPS1 siRNA (Human) - CRH6426 from Cohesion Biosciences
|
||||||||
RALGPS1 - MBS8231030 from MyBioSource
|
||||||||
shRNA set against Human RALGPS1 (NM_014636.2) - SHH389356 from Creative biogene
|
||||||||
RALGPS1 shRNA Plasmid (Human) - CHH6426 from Cohesion Biosciences
|
||||||||
RALGPS1 miRNA 3'UTR clone - MiUTR4H-TG07309 from Creative biogene
|