Gene Symbol | Mfng |
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Entrez Gene | 17305 |
Alt Symbol | AW546563 |
Species | Mouse |
Gene Type | protein-coding |
Description | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
Other Description | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase|beta-1,3-N-acetylglucosaminyltransferase manic fringe|manic fringe homolog |
Swissprots | O09008 |
Accessions | EDL29700 O09008 AF015769 AAB71669 AK143523 BAE25415 BC010983 AAH10983 U94349 AAC53260 XM_006520551 XP_006520614 XM_006520552 XP_006520615 XR_875250 NM_008595 NP_032621 |
Function | Glycosyltransferase involved in the elongation of O- linked ligands to activate Notch signaling. Possesses fucose- specific beta-1,3-N-acetylglucosaminyltransferase activity. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Top Pathways | Other types of O-glycan biosynthesis, Notch signaling pathway |
Manic Fringe CRISPR/Cas9 KO Plasmid (m) - sc-421640 from Santa Cruz Biotechnology
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Manic Fringe HDR Plasmid (m) - sc-421640-HDR from Santa Cruz Biotechnology
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Manic Fringe Double Nickase Plasmid (m) - sc-421640-NIC from Santa Cruz Biotechnology
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Manic Fringe Double Nickase Plasmid (m2) - sc-421640-NIC-2 from Santa Cruz Biotechnology
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Manic Fringe CRISPR Activation Plasmid (m) - sc-421640-ACT from Santa Cruz Biotechnology
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Manic Fringe CRISPR Activation Plasmid (m2) - sc-421640-ACT-2 from Santa Cruz Biotechnology
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Manic Fringe Lentiviral Activation Particles (m) - sc-421640-LAC from Santa Cruz Biotechnology
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Manic Fringe Lentiviral Activation Particles (m2) - sc-421640-LAC-2 from Santa Cruz Biotechnology
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Manic Fringe siRNA (m) - sc-39493 from Santa Cruz Biotechnology
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Manic Fringe shRNA Plasmid (m) - sc-39493-SH from Santa Cruz Biotechnology
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Manic Fringe shRNA (m) Lentiviral Particles - sc-39493-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU026341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN35519 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND35519 from Sigma-Aldrich
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MFNG siRNA (Mouse) - CRM2530 from Cohesion Biosciences
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shRNA set against Mouse Mfng (NM_008595.2) - SHH341131 from Creative biogene
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shRNA set against Mouse Mfng(NM_008595.2) - SHH186725 from Creative biogene
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Mouse MFNG siRNA - orb282006 from Biorbyt
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MFNG shRNA Plasmid (Mouse) - CHM2530 from Cohesion Biosciences
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MFNG miRNA 3'UTR clone - MiUTR1M-07083 from Creative biogene
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