Gene Symbol | HEXA |
---|---|
Entrez Gene | 3073 |
Alt Symbol | TSD |
Species | Human |
Gene Type | protein-coding |
Description | hexosaminidase A (alpha polypeptide) |
Other Description | N-acetyl-beta-glucosaminidase subunit alpha|beta-N-acetylhexosaminidase subunit alpha|beta-hexosaminidase subunit alpha|hexosaminidase subunit A |
Swissprots | Q6AI32 B4DKE7 Q53HS8 E7ENH7 P06865 |
Accessions | AAB00965 AAD13932 AER36552 BAL04456 BAL04457 BAL04458 BAL04459 BAL04460 BAL04461 BAL04462 BAL04463 EAW77902 P06865 AK222502 BAD96222 AK296528 BAG59159 AK297678 BAG60039 AK301000 BAG62619 AK301138 BAG62730 AK307770 AK310154 BC001138 AAH01138 BC018927 AAH18927 BC021030 AAH21030 BC034424 BC084537 AAH84537 BP356349 BX537989 CR627386 CAH10482 DC356933 DQ892696 ABM83622 EU176728 ABW03529 J04178 M13520 AAA51827 S61298 AAD13927 S76980 AAB33748 S76982 AAD14242 S76984 AAD14243 S77043 AAD14246 NM_000520 NP_000511 |
Function | Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides. The form S has no measurable activity. |
Subcellular Location | Lysosome. |
Top Pathways | Lysosome, Amino sugar and nucleotide sugar metabolism, Glycosphingolipid biosynthesis - globo series, Other glycan degradation, Glycosaminoglycan degradation |
HEXA (D-2) - sc-376777 from Santa Cruz Biotechnology
|
||||||||||
HEXA (E-2) - sc-376735 from Santa Cruz Biotechnology
|
||||||||||
HEXA (C-17) - sc-48527 from Santa Cruz Biotechnology
|
||||||||||
HEXA (C-14) - sc-48526 from Santa Cruz Biotechnology
|
||||||||||
HEXA (H-40) - sc-134577 from Santa Cruz Biotechnology
|
||||||||||
HEXA (M-15) - sc-48528 from Santa Cruz Biotechnology
|
||||||||||
HEXA (N-19) - sc-48530 from Santa Cruz Biotechnology
|
||||||||||
Anti-HEXA antibody - ab93111 from Abcam
|
||||||||||
Anti-HEXA antibody - ab70083 from Abcam
|
||||||||||
Anti-HEXA antibody [3F10] - ab128488 from Abcam
|
||||||||||
Anti-HEXA antibody - N-terminal - ab91624 from Abcam
|
||||||||||
Anti-HEXA Antibody (clone 3F10) - LS-C169185 from LifeSpan Bioscience
|
||||||||||
Anti-HEXA Antibody (aa318-529) - LS-C314424 from LifeSpan Bioscience
|
||||||||||
Anti-HEXA Antibody - LS-C334185 from LifeSpan Bioscience
|
||||||||||
Anti-HEXA Antibody (aa315-343) - LS-C166844 from LifeSpan Bioscience
|
||||||||||
Anti-HEXA Antibody (aa191-207) - LS-C312933 from LifeSpan Bioscience
|
||||||||||
Anti-HEXA Antibody (aa513-529) - LS-C343900 from LifeSpan Bioscience
|
||||||||||
Anti-HEXA Antibody (clone 3D1) - LS-C197404 from LifeSpan Bioscience
|
||||||||||
Anti-HEXA Antibody (aa431-480) IHC-plus⢠- LS-B6959 from LifeSpan Bioscience
|
||||||||||
Anti-HEXA Antibody (aa142-170) IHC-plus⢠- LS-B9894 from LifeSpan Bioscience
|
||||||||||
Anti-HEXA Antibody (aa1-529, clone 1D4B) - LS-C189807 from LifeSpan Bioscience
|
||||||||||
Anti-HEXA Antibody (Internal, AP) - LS-C278080 from LifeSpan Bioscience
|
||||||||||
Anti-HEXA Antibody (Internal, APC) - LS-C278082 from LifeSpan Bioscience
|
||||||||||
Anti-HEXA Antibody (Internal, Biotin) - LS-C278083 from LifeSpan Bioscience
|
||||||||||
Anti-HEXA Antibody (Internal, Azide-free, HRP) - LS-C278085 from LifeSpan Bioscience
|