Ivermectin activates a7 nicotinic AChR heterologously expressed in Xenopus oocytes. Current traces of a7 nicotinic AChR at -80mV holding potential. Currents were elicited by applications 10 µM acetylcholine every 50 seconds. Increases of these induced currents were achieved upon perfusion of 10 µM Ivermectin (ab141813), as indicated by the horizontal bar.

Ivermectin activates a7 nicotinic AChR heterologously expressed in Xenopus oocytes. Current traces of a7 nicotinic AChR at -80mV holding potential. Currents were elicited by applications 10 µM acetylcholine every 50 seconds. Increases of these induced currents were achieved upon perfusion of 10 µM Ivermectin (ab141813), as indicated by the horizontal bar.


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