Recombinant Human IL-23, CF

Name Recombinant Human IL-23, CF
Supplier R&D Systems
Catalog 1290-IL-010/CF
Category Protein
Nature Recombinant
Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived
Purity >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
SwissProt/Accession P29460 (p40) & AAG37232(p19)
Gene IL23A
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Product References

Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are - Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are

Ramesh R, Kozhaya L, McKevitt K, Djuretic IM, Carlson TJ, Quintero MA, McCauley JL, Abreu MT, Unutmaz D, Sundrud MS. J Exp Med. 2014 Jan 13;211(1):89-104.

Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV - Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV

Li H, Richert-Spuhler LE, Evans TI, Gillis J, Connole M, Estes JD, Keele BF, Klatt NR, Reeves RK. PLoS Pathog. 2014 Dec 11;10(12):e1004551.

Kynurenine 3-monooxygenase mediates inhibition of Th17 differentiation via - Kynurenine 3-monooxygenase mediates inhibition of Th17 differentiation via

Stephens GL, Wang Q, Swerdlow B, Bhat G, Kolbeck R, Fung M. Eur J Immunol. 2013 Jul;43(7):1727-34.

C3a modulates IL-1beta secretion in human monocytes by regulating ATP efflux and - C3a modulates IL-1beta secretion in human monocytes by regulating ATP efflux and

Asgari E, Le Friec G, Yamamoto H, Perucha E, Sacks SS, Kohl J, Cook HT, Kemper C. Blood. 2013 Nov 14;122(20):3473-81.

Complementary IL-23 and IL-27 anti-tumor activities cause strong inhibition of - Complementary IL-23 and IL-27 anti-tumor activities cause strong inhibition of

Cocco C, Di Carlo E, Zupo S, Canale S, Zorzoli A, Ribatti D, Morandi F, Ognio E, Airoldi I. Leukemia. 2012 Jun;26(6):1365-74.

Laminin-411 is a vascular ligand for MCAM and facilitates TH17 cell entry into - Laminin-411 is a vascular ligand for MCAM and facilitates TH17 cell entry into

Flanagan K, Fitzgerald K, Baker J, Regnstrom K, Gardai S, Bard F, Mocci S, Seto P, You M, Larochelle C, Prat A, Chow S, Li L, Vandevert C, Zago W, Lorenzana C, Nishioka C, Hoffman J, Botelho R, Willits C, Tanaka K, Johnston J, Yednock T. PLoS One. 2012;7(7):e40443.

IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory - IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory

Corvaisier M, Delneste Y, Jeanvoine H, Preisser L, Blanchard S, Garo E, Hoppe E, Barre B, Audran M, Bouvard B, Saint-Andre JP, Jeannin P. PLoS Biol. 2012;10(9):e1001395.

The IL23R R381Q gene variant protects against immune-mediated diseases by - The IL23R R381Q gene variant protects against immune-mediated diseases by

Di Meglio P, Di Cesare A, Laggner U, Chu CC, Napolitano L, Villanova F, Tosi I, Capon F, Trembath RC, Peris K, Nestle FO. PLoS One. 2011 Feb 22;6(2):e17160.

Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased - Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased

Bowness P, Ridley A, Shaw J, Chan AT, Wong-Baeza I, Fleming M, Cummings F, McMichael A, Kollnberger S. J Immunol. 2011 Feb 15;186(4):2672-80.

B cells as a therapeutic target for IFN-beta in relapsing-remitting multiple - B cells as a therapeutic target for IFN-beta in relapsing-remitting multiple

Ramgolam VS, Sha Y, Marcus KL, Choudhary N, Troiani L, Chopra M, Markovic-Plese S. J Immunol. 2011 Apr 1;186(7):4518-26.