Recombinant Human TIM-3 Fc Chimera, CF

• Supplier: R&D Systems
• Catalog: 2365-TM-050
• Category: Protein
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• SwissProt/Accession: Q8TDQ0
• Gene: HAVCR2

Product References

Blockade of Tim-3 signaling restores the virus-specific CD8(+) T-cell response in - Blockade of Tim-3 signaling restores the virus-specific CD8(+) T-cell response in

Wu W, Shi Y, Li S, Zhang Y, Liu Y, Wu Y, Chen Z. Eur J Immunol. 2012 May;42(5):1180-91.

Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic - Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic

Nebbia G, Peppa D, Schurich A, Khanna P, Singh HD, Cheng Y, Rosenberg W, Dusheiko G, Gilson R, ChinAleong J, Kennedy P, Maini MK. PLoS One. 2012;7(10):e47648.

Dysregulation of TIM-3-galectin-9 pathway in the cystic fibrosis airways. - Dysregulation of TIM-3-galectin-9 pathway in the cystic fibrosis airways.

Vega-Carrascal I, Reeves EP, Niki T, Arikawa T, McNally P, O'Neill SJ, Hirashima M, McElvaney NG. J Immunol. 2011 Mar 1;186(5):2897-909.

Gene-trap mutagenesis identifies mammalian genes contributing to intoxication by - Gene-trap mutagenesis identifies mammalian genes contributing to intoxication by

Ivie SE, Fennessey CM, Sheng J, Rubin DH, McClain MS. PLoS One. 2011 Mar 11;6(3):e17787.