Recombinant Human Gremlin, CF

• Supplier: R&D Systems
• Catalog: 5190-GR-050
• Category: Protein
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived, Lys25-Asp184, with a C-terminal 10-His tag
• Purity: >90%, by SDS-PAGE with silver staining.
• SwissProt/Accession: O60565
• Gene: GREM1

Product References

Gremlin-1 induces BMP-independent tumor cell proliferation, migration, and - Gremlin-1 induces BMP-independent tumor cell proliferation, migration, and

Kim M, Yoon S, Lee S, Ha SA, Kim HK, Kim JW, Chung J. PLoS One. 2012;7(4):e35100.

Widespread potential for growth-factor-driven resistance to anticancer kinase - Widespread potential for growth-factor-driven resistance to anticancer kinase

Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J. Nature. 2012 Jul 26;487(7408):505-9.

Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2. - Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2.

Mitola S, Ravelli C, Moroni E, Salvi V, Leali D, Ballmer-Hofer K, Zammataro L, Presta M. Blood. 2010 Nov 4;116(18):3677-80.