Recombinant Human Osteopontin (OPN)

• Supplier: R&D Systems
• Catalog: 1433-OP-050
• Category: Protein
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived, Ile17-Asn300, with a C-terminal 6-His tag
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• SwissProt/Accession: NP_000573.1
• Gene: SPP1

Product References

OPN induces FoxM1 expression and localization through ERK 1/2, AKT, and p38 - OPN induces FoxM1 expression and localization through ERK 1/2, AKT, and p38

Xie Y, Li Y, Kong Y. Int J Mol Sci. 2014 Dec 16;15(12):23345-58.

Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin - Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin

Barros NM, Hoac B, Neves RL, Addison WN, Assis DM, Murshed M, Carmona AK, McKee MD. J Bone Miner Res. 2013 Mar;28(3):688-99.

Osteopontin induces growth of metastatic tumors in a preclinical model of - Osteopontin induces growth of metastatic tumors in a preclinical model of

Shojaei F, Scott N, Kang X, Lappin PB, Fitzgerald AA, Karlicek S, Simmons BH, Wu A, Lee JH, Bergqvist S, Kraynov E. J Exp Clin Cancer Res. 2012 Mar 23;31:26.

Secreted osteopontin is highly polymerized in human airways and fragmented in - Secreted osteopontin is highly polymerized in human airways and fragmented in

Arjomandi M, Frelinger J, Donde A, Wong H, Yellamilli A, Raymond W. PLoS One. 2011;6(10):e25678.

Elevated serum osteopontin levels and genetic polymorphisms of osteopontin are - Elevated serum osteopontin levels and genetic polymorphisms of osteopontin are

Chu M, Yang P, Hu R, Hou S, Li F, Chen Y, Kijlstra A. Invest Ophthalmol Vis Sci. 2011 Sep 9;52(10):7084-9.

Osteopontin deficiency protects against airway remodeling and hyperresponsiveness - Osteopontin deficiency protects against airway remodeling and hyperresponsiveness

Simoes DC, Xanthou G, Petrochilou K, Panoutsakopoulou V, Roussos C, Gratziou C. Am J Respir Crit Care Med. 2009 May 15;179(10):894-902. doi:

Adhesion of human haematopoietic (CD34+) stem cells to human liver compartments - Adhesion of human haematopoietic (CD34+) stem cells to human liver compartments

Crosby HA, Lalor PF, Ross E, Newsome PN, Adams DH. J Hepatol. 2009 Oct;51(4):734-49.

Heterozygous disruption of the PTEN promotes intestinal neoplasia in APCmin/+ - Heterozygous disruption of the PTEN promotes intestinal neoplasia in APCmin/+

Shao J, Washington MK, Saxena R, Sheng H. Carcinogenesis. 2007 Dec;28(12):2476-83. Epub 2007 Aug 11.