SPP1

Gene Symbol	SPP1
Entrez Gene	6696
Alt Symbol	BNSP, BSPI, ETA-1, OPN
Species	Human
Gene Type	protein-coding
Description	secreted phosphoprotein 1
Other Description	SPP1/CALPHA1 fusion|early T-lymphocyte activation 1|nephropontin|osteopontin|osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein|secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)|urinary stone protein|uropontin
Swissprots	Q8NBK2 Q567T5 Q15683 B2RDA1 Q15682 Q4W597 Q15681 Q96IZ1 P10451
Accessions	AAA86886 AAY41035 BAA03554 CAX69239 CBX54353 EAX06004 EAX06005 EAX06006 EAX06007 EAX06008 EAX06009 EAX06010 P10451 AA665210 AB209987 BAE45628 AB469789 BAH58215 AF052124 AAC28619 AK057738 AK075463 BAC11635 AK290090 BAF82779 AK290104 BAF82793 AK295491 BAH12087 AK296035 BAG58801 AK315461 BAG37848 AM392768 CAL37646 AM392898 CAL37776 AY956318 AAX59003 BC007016 AAH07016 BC017387 AAH17387 BC022844 AAH22844 BC093033 AAH93033 BF699765 BX648003 CB117856 D28759 BAA05949 D28760 BAA05950 D28761 BAA05951 DA419665 DQ839491 ABI63352 DQ846870 ABI63357 DQ846871 ABI63358 DQ892544 ABM83470 DQ895755 ABM86681 EU831940 ACE87381 EU832035 ACE86697 HQ874460 AEA49027 HQ874461 AEA49028 J04765 AAA59974 JF412666 AEA49030 JF412667 AEA49031 M83248 AAA17675 X13694 CAA31984 NM_000582 NP_000573 NM_001040058 NP_001035147 NM_001040060 NP_001035149 NM_001251829 NP_001238758 NM_001251830 NP_001238759
Function	Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.
Subcellular Location	Secreted.
Tissue Specificity	Bone. Found in plasma.
Top Pathways	Focal adhesion, ECM-receptor interaction, Toll-like receptor signaling pathway, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Osteopontin full length protein - ab92964 from Abcam Category Protein Source E. coli Species Human

Human Osteopontin full length protein - ab152079 from Abcam Category Protein Source HEK 293 cells Species Human

Human Osteopontin full length protein - ab173997 from Abcam Category Protein Source HEK 293 cells Species Human

Human Osteopontin full length protein - ab194168 from Abcam Category Protein Source Mammalian Species Human

Human Osteopontin full length protein - ab87460 from Abcam Category Protein Source E. coli Species Human

Human Osteopontin peptide - ab42272 from Abcam Category Peptide Species Human

Human Osteopontin peptide - ab42273 from Abcam Category Peptide Species Human

Human Osteopontin peptide - ab65665 from Abcam Category Peptide

Osteopontin peptide - ab189325 from Abcam Category Peptide

Osteopontin peptide (288-299) (Carboxyterminal end) - ab45753 from Abcam Category Peptide Species Human

OPN-ab-Antibody-N-term-Blocking-peptide - BP11567a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SPP1-Antibody-C-term-Blocking-Peptide - BP6555b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Osteopontin recombinant protein - GTX53843 from GeneTex Category Protein Prices $199.00 Sizes 50 μg Source HEK293 cells

Osteopontin/SPP1 blocking peptide - GTX89519-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

Recombinant Mouse Osteopontin (OPN) - 441-OP-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Leu17-Asn294 (Glu99Gly), with a C-terminal 6-His tag

Recombinant Mouse Osteopontin (OPN) - 441-OP-200 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Leu17-Asn294 (Glu99Gly), with a C-terminal 6-His tag

Recombinant Mouse Osteopontin (OPN), CF - 441-OP-050/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Leu17-Asn294 (Glu99Gly), with a C-terminal 6-His tag

Recombinant Mouse Osteopontin (OPN), CF - 441-OP-200/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Leu17-Asn294 (Glu99Gly), with a C-terminal 6-His tag

Recombinant Human Osteopontin (OPN) - 1433-OP-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Ile17-Asn300, with a C-terminal 6-His tag

Recombinant Human Osteopontin (OPN), CF - 1433-OP-050/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Ile17-Asn300, with a C-terminal 6-His tag

Bovine Osteopontin (OPN) - 109-OP-050 from R&D Systems Category Protein Source Bovine milk-derived,

Bovine Osteopontin (OPN), CF - 109-OP-050/CF from R&D Systems Category Protein Source Bovine milk-derived,

Recombinant human Osteopontin (OPCA00675) - OPCA00675 from Aviva Systems Biology Category Protein Prices $198.00 Sizes 50 µg Species Human

SPP1 Protein (OPPA01898) - OPPA01898 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

SYNTHETIC Human OSTEOPONTIN Protein (OPSA10578) - OPSA10578 from Aviva Systems Biology Category Protein Prices $155.00 Sizes 50 µg Species Human

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