Recombinant Human Osteoprotegerin/TNFRSF11B, CF

• Supplier: R&D Systems
• Catalog: 185-OS-025/CF
• Category: Protein
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived, Glu22-Leu401
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• SwissProt/Accession: AAB53709.1
• Gene: TNFRSF11B

Product References

Widespread potential for growth-factor-driven resistance to anticancer kinase - Widespread potential for growth-factor-driven resistance to anticancer kinase

Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J. Nature. 2012 Jul 26;487(7408):505-9.

Interleukin-32 promotes osteoclast differentiation but not osteoclast activation. - Interleukin-32 promotes osteoclast differentiation but not osteoclast activation.

Mabilleau G, Sabokbar A. PLoS One. 2009;4(1):e4173.

Osteoprotegerin decreases human osteoclast apoptosis by inhibiting the TRAIL - Osteoprotegerin decreases human osteoclast apoptosis by inhibiting the TRAIL

Chamoux E, Houde N, L'Eriger K, Roux S. J Cell Physiol. 2008 Aug;216(2):536-42.

Attenuation of bone mass and increase of osteoclast formation in decoy receptor 3 - Attenuation of bone mass and increase of osteoclast formation in decoy receptor 3

Tang CH, Hsu TL, Lin WW, Lai MZ, Yang RS, Hsieh SL, Fu WM. J Biol Chem. 2007 Jan 26;282(4):2346-54. Epub 2006 Nov 10.

Impairment of the antifibrotic effect of hepatocyte growth factor in lung - Impairment of the antifibrotic effect of hepatocyte growth factor in lung

Bogatkevich GS, Ludwicka-Bradley A, Highland KB, Hant F, Nietert PJ, Singleton CB, Feghali-Bostwick CA, Silver RM. Arthritis Rheum. 2007 Jul;56(7):2432-42.

Selective targeting of death receptor 5 circumvents resistance of MG-63 - Selective targeting of death receptor 5 circumvents resistance of MG-63

Locklin RM, Federici E, Espina B, Hulley PA, Russell RG, Edwards CM. Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3219-28. Epub 2007 Dec 7.

Activation of the p53 pathway down-regulates the osteoprotegerin expression and - Activation of the p53 pathway down-regulates the osteoprotegerin expression and

Secchiero P, Corallini F, Rimondi E, Chiaruttini C, di Iasio MG, Rustighi A, Del Sal G, Zauli G. Blood. 2008 Feb 1;111(3):1287-94. Epub 2007 Nov 13.