Recombinant Human R-Spondin 4

• Supplier: R&D Systems
• Catalog: 4575-RS-025
• Category: Protein
• Nature: Recombinant
• Source: Chinese Hamster Ovary cell line, CHO-derived, Met1-Pro234
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• SwissProt/Accession: Q2I0M5
• Gene: RSPO4

Product References

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner. - ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.

Hao HX, Xie Y, Zhang Y, Charlat O, Oster E, Avello M, Lei H, Mickanin C, Liu D, Ruffner H, Mao X, Ma Q, Zamponi R, Bouwmeester T, Finan PM, Kirschner MW, Porter JA, Serluca FC, Cong F. Nature. 2012 Apr 29;485(7397):195-200.

Widespread potential for growth-factor-driven resistance to anticancer kinase - Widespread potential for growth-factor-driven resistance to anticancer kinase

Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J. Nature. 2012 Jul 26;487(7408):505-9.