Human Fpg protein

• Supplier: Biorbyt
• Catalog: orb49167
• Category: Protein
• Prices: $323.00, $485.00, $1,904.00, $2,695.00
• Sizes: 10 μg, 50 μg, 500 μg, 1 mg
• Applications: SDS-PAGE
• Species Reactivities: Escherichia coli
• Purity: >95% as determined by reducing SDS-PAGE.
• Endotoxin: Less than 0.1 ng/μg (1 IEU/μg).
• Gene: mutM
• Sequence: MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLTHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQKLEHHHHHH
• Description: Recombinant E. coli Form amidopyrimidineDNA Glycosylase/Fpg is produced with our E. coli expression system. The target protein is expressed with sequence (Met1Lys269) of E. coli Fpg.Fpg is a DNA glycosylase that releases damaged bases preferentially from duplex DNA. It has an associated class I AP (apurinic/apyrimidinic) lyase activity.Fpg Cleaves the DNA backbone to generate a singlestrand break at the site of the removed base, The COP bond 3' to the apurinic or apyrimidinic site in DNA is broken by a betaelimination reaction, leaving 3' and 5' phosphoryl groups.