mutM

Gene Symbol	mutM
Entrez Gene	946765
Alt Symbol	ECK3625, JW3610, fpg
Species	Escherichia coli
Gene Type	protein-coding
Description	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase
Other Description	-
Swissprots	P05523 Q2M7U9
Accessions	AAB18612 AAC76659 NP_418092
Function	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG) and its derivatives such as guanidinohydantoin:C and spiroiminodihydantoin:C, however it also acts on thymine glycol:G, 5,6-dihydrouracil:G and 5-hydroxyuracil:G. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Cleaves ssDNA containing an AP site. {ECO:0000269|PubMed:1689309, ECO:0000269|PubMed:20031487}.
Top Pathways	Base excision repair

• Assays/Kits
• Proteins/Peptides

E. coli mutM full length protein - ab124310 from Abcam Category Protein Prices $345.00 Sizes 50 µg Source E. coli Species Escherichia coli

Human Fpg protein - orb49167 from Biorbyt Category Protein Prices $323.00, $485.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Escherichia coli

mutM protein (His tag) - 80R-2192 from Fitzgerald Category Protein Prices $365.00 Sizes 50 µg Source E.coli

mutM (1-269, His-tag) - AR50273PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli

mutM (1-269, His-tag) - AR50273PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli

mutM, 1-269 aa, E.coli, His tag, E.coli - 01-P1448 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Escherichia coli

Recombinant E.coli mutM - mutM-52E from Creative Biomart Category Protein Source E. coli Species Escherichia coli

E.coli Fpg Protein - 4040-100-EB from Nordic BioSite Category Protein Species Escherichia coli

Recombinant Escherichia coli Formamidopyrimidine-DNA glycosylase(mutM) - CSB-YP361544ENV CSB-EP361544ENV CSB-BP361544ENV CSB-MP361544ENV from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Escherichia coli

mutM, 1-269aa, E.coli, His tag, E.coli - ATGP1448 from ATGen Category Protein Prices $105.00, $320.00, $960.00 Sizes 10 µg, 50 µg, 250 µg Species Escherichia coli

Formamidopyrimidine-DNA Glycosylase , Recombinant Protein - MBS144826 from MyBioSource Category Protein Prices $140.00, $205.00, $5,015.00 Sizes 2 µg, 10 µg, 1 mg Source E Coli

Formamidopyrimidine-DNA glycosylase (mutM), Recombinant Protein - MBS1142311 from MyBioSource Category Protein Prices $1,020.00, $1,020.00, $1,250.00, $1,250.00, $1,575.00, $1,575.00, $2,040.00, $2,040.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Escherichia coli

Formamidopyrimidine-DNA Glycosylase E.Coli Recombinant - 228-20536-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Escherichia coli

mutM, Recombinant Protein - MBS204686 from MyBioSource Category Protein Prices $375.00, $925.00 Sizes 50 µg, 250 µg Source E Coli Species Escherichia coli

E. coli Fpg protein - orb419919 from Biorbyt Category Protein Species Escherichia coli

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