Sirtuin 1 enzyme

• Supplier: Biorbyt
• Catalog: orb108391
• Category: Protein
• Prices: $553.00
• Sizes: 100 μg
• Applications: SDS-PAGE
• Species Reactivities: Human
• Source: E.coli
• Purity: > 60% pure
• Bioactivity: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. 10.2 pmol/min/μg. One U =1 pmol/min, Assay condition: 25 mM Tris/HCl, pH 8.0, 137 mM NaCl, 2.7 mM KCl, 1 mM MgCl2, and 0.1 mg/ml BSA, 20 μM HDAC substrate 1, 500 μM NAD+
• Gene: SIRT1
• Description: Sirtuin 1 is a NAD dependent deacetylase active enzyme plays key role to regulate apoptosis and muscle differentiation by deacetylating key proteins,as well as it links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy.