Name |
Human Maspin protein
|
Supplier |
Biorbyt
|
Catalog |
orb107777
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Category |
Protein
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Prices |
$221.00, $357.00, $553.00, $910.00
|
Sizes |
5 μg, 20 μg, 100 μg, 250 μg
|
Applications |
SDS-PAGE HPLC
|
Species Reactivities |
Human
|
Source |
E.coli
|
Purity |
> 95% by SDS-PAGE and HPLC analyses
|
Gene |
SERPINB5
|
Sequence |
MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHFENVKDIPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVDFKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFPESETKECPFRLNKT DTKPVQMMNM EATFCMGNID SINCKIIELP FQNKHLSMFI LLPKDVEDESTGLEKIEKQL NSESLSQWTN PSTMANAKVK LSIPKFKVEK MIDPKACLEN LGLKHIFSEDTSDFSGMSET KGVALSNVIH KVCLEITEDG GDSIEVPGAR ILQHKDELNA DHPFIYIIRHNKTRNIIFFG KFCSP
|
Description |
Mammary serine protease inhibitor (Maspin) is a non-inhibitory serpin that is expressed predominantly in normal mammaryepithelial cells but at significantly reduced levels or absent in most breast carcinomas. It has the ability to block the growth,invasiveness, and metastatic potential of breast and lung tumors. This anti-tumor activity is achieved, in part, by the ability ofMaspin to inhibit angiogenesis and to preferentially promote apoptosis of tumor cells.
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