Human Maspin protein

Name Human Maspin protein
Supplier Biorbyt
Catalog orb107777
Category Protein
Prices $221.00, $357.00, $553.00, $910.00
Sizes 5 μg, 20 μg, 100 μg, 250 μg
Applications SDS-PAGE HPLC
Species Reactivities Human
Source E.coli
Purity > 95% by SDS-PAGE and HPLC analyses
Gene SERPINB5
Sequence MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHFENVKDIPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVDFKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFPESETKECPFRLNKT DTKPVQMMNM EATFCMGNID SINCKIIELP FQNKHLSMFI LLPKDVEDESTGLEKIEKQL NSESLSQWTN PSTMANAKVK LSIPKFKVEK MIDPKACLEN LGLKHIFSEDTSDFSGMSET KGVALSNVIH KVCLEITEDG GDSIEVPGAR ILQHKDELNA DHPFIYIIRHNKTRNIIFFG KFCSP
Description Mammary serine protease inhibitor (Maspin) is a non-inhibitory serpin that is expressed predominantly in normal mammaryepithelial cells but at significantly reduced levels or absent in most breast carcinomas. It has the ability to block the growth,invasiveness, and metastatic potential of breast and lung tumors. This anti-tumor activity is achieved, in part, by the ability ofMaspin to inhibit angiogenesis and to preferentially promote apoptosis of tumor cells.
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