Gene Symbol | SERPINB5 |
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Entrez Gene | 5268 |
Alt Symbol | PI5, maspin |
Species | Human |
Gene Type | protein-coding |
Description | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
Other Description | PI-5|peptidase inhibitor 5|protease inhibitor 5 (maspin)|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5|serpin B5 |
Swissprots | Q6N0B4 P36952 Q8WW89 B2R6Y4 |
Accessions | EAW63145 EAW63146 EAW63147 EAW63148 P36952 AK301667 BAG63141 AK312765 BAG35631 AL602439 BC020713 AAH20713 BM955647 BX640597 CAE45703 CV575332 U04313 AAA18957 XM_006722483 XP_006722546 NM_002639 NP_002630 |
Function | Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. |
Subcellular Location | Secreted, extracellular space. |
Tissue Specificity | Normal mammary epithelial cells. |
Top Pathways | p53 signaling pathway, MicroRNAs in cancer |
Human MASPIN full length protein - ab201374 from Abcam
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Human MASPIN full length protein - ab86689 from Abcam
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Human MASPIN full length protein - ab125796 from Abcam
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Human MASPIN peptide - ab24350 from Abcam
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MASPIN peptide - ab44631 from Abcam
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MASPIN peptide - ab44633 from Abcam
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MASPIN peptide - ab44798 from Abcam
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SERPINB5 / Maspin Antibody Blocking Peptide - LS-E1414 from LifeSpan Bioscience
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Recombinant Human Serpin B5/Maspin Protein - NBP2-34953 from Novus Biologicals
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Serpin B5/Maspin Blocking Peptide - NB110-97377PEP from Novus Biologicals
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Serpin B5/Maspin Recombinant Protein - H00005268-P01 from Novus Biologicals
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Recombinant Human Serpin B5/Maspin Protein - NBC1-28767 from Novus Biologicals
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Maspin-Antibody-Center-Blocking-peptide - BP12083c from Abgent, a WuXi AppTec company
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Maspin Recombinant Protein - GTX48160-PRO from GeneTex
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SERPINB5 Protein (OOPA00212) - OOPA00212 from Aviva Systems Biology
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SERPINB5 Protein (OPPA01951) - OPPA01951 from Aviva Systems Biology
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Human SERPINB5 protein - orb168787 from Biorbyt
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Human Serpin B5 protein - orb163520 from Biorbyt
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Human SERPINB5 protein (His Tag) - orb81359 from Biorbyt
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Human Maspin protein - orb107777 from Biorbyt
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Maspin protein - 30R-AM043 from Fitzgerald
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Maspin protein (His tag) - 80R-1158 from Fitzgerald
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SERPINB5 Blocking Peptide - 33R-6892 from Fitzgerald
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Serpin B5 Blocking Peptide - abx063080 from Abbexa
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SERPINB5 - H00005268-P01-10 from Acris Antibodies
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