Active human ITCH/AIP4 full length protein

Name Active human ITCH/AIP4 full length protein
Supplier Abcam
Catalog ab190328
Category Protein
Prices $572.00
Sizes 100 µg
Applications SDS-PAGE FA
Species Reactivities Human
Nature Recombinant
Source E. coli
Purity >90% by SDS-PAGE.
Bioactivity This untagged, ITCH/AIP4 isoform 2 recombinant protein demonstrates strong autoubiquitination activity in vitro. Typical enzyme concentration to support conjugation in vitro is 0.1-0.5 µM depending on experimental conditions.
SwissProt/Accession Q96J02
Gene ITCH
Residue 1 to 862
Sequence MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQ SKKTEKCNNT NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTA ALDIYETLKSNNMKLEEVVVTL QLGGDKEPTETIGDLSICLDGLQLES EVVTNGETTCSESASQNDDGSRSKDETRVSTNGS DDPEDAGAGENRRV SGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD GS STGSLPPTNTNTNTSEGATSGLIIPLTISGGSGPRPLNPVTQAPLPPGWE QRVDQHGR VYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFT RTTTWQRPTLESVRNYEQWQ LQRSQLQGAMQQFNQRFIYGNQDLFATS QSKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT RITQWEDPRSQGQLNE KPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ IAYV RDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRR RLWVIF PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQ INPASYINPDHLKYFRFI GRFIAMALFHGKFIDTGFSLPFYKRILNKP VGLKDLESIDPEFYNSLIWVKENNIEECDL EMYFSVDKEILGEIKSHD LKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF NEILPQ QYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYARTSKQIMWFWQFVK EIDN EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWL PRSHTCFNRLDLPPYK SYEQLKEKLLFAIEETEGFGQE
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