| Name |
Active human LRRK2 protein fragment
|
| Supplier |
Abcam
|
| Catalog |
ab196116
|
| Category |
Protein
|
| Prices |
$648.00
|
| Sizes |
10 µg
|
| Applications |
SDS-PAGE FA
|
| Species Reactivities |
Human
|
| Nature |
Recombinant
|
| Source |
Baculovirus infected sf9 cells
|
| Tag/Conjugation |
GST tag N-Terminus
|
| Purity |
>= 5 % by SDS-PAGE.
|
| Bioactivity |
Specific Activity: 34 pmol/min/µg A 25 µl kinase reaction is conducted in a buffer containing 40 mM Tris-HCl (pH 7.5), 20 mM MgCl2, 100 µM ATP, and 0.2 mg/ml LRRKtide for 60 minutes at 30°C. ATP reduction is detected.
|
| SwissProt/Accession |
Q5S007
|
| Gene |
LRRK2
|
| Residue |
960 to 2527
|
| Sequence |
RSSKLQSHMRHSDSISSLASEREYITSLDLSANELRDIDALSQKCCISVH LEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSC IANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVEKL EQLILEGNKISGICSPLRLKELKILNLSKNHISSLSENFLEACPKVESFS ARMNFLAAMPFLPPSMTILKLSQNKFSCIPEAILNLPHLRSLDMSSNDIQ YLPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKE IPPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELHLNFDFK HIGCKAKDIIRFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKK SDLGMQSATVGIDVKDWPIQIRDKRKRDLVLNVWDFAGREEFYSTHPHFM TQRALYLAVYDLSKGQAEVDAMKPWLFNIKARASSSPVILVGTHLDVSDE KQRKACMSKITKELLNKRGFPAIRDYHFVNATEESDALAKLRKTIINESL NFKIRDQLVVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKRLLQLVRE NQLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKIMAQ ILTVKVEGCPKHPKGIISRRDVEKFLSKKRKFPKNYMSQYFKLLEKFQIA LPIGEEYLLVPSSLSDHRPVIELPHCENSEIIIRLYEMPYFPMGFWSRLI NRLLEISPYMLSGRERALRPNRMYWRQGIYLNWSPEAYCLVGSEVLDNHP ESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDICGEGETLLK KWALYSFNDGEEHQKILLDDLMKKAEEGDLLVNPDQPRLTIPISQIAPDL ILADLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFN KHTSLRLLRQELVVLCHLHHPSLISLLAAGI
|
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