| Name |
Active human PI 3 Kinase p110 alpha + PI 3 kinase p85 alpha full length protein
|
| Supplier |
Abcam
|
| Catalog |
ab198145
|
| Category |
Protein
|
| Prices |
$837.00
|
| Sizes |
20 µg
|
| Applications |
FA SDS-PAGE
|
| Species Reactivities |
Human
|
| Nature |
Recombinant
|
| Source |
Baculovirus infected sf9 cells
|
| Tag/Conjugation |
DDDDK tag N-Terminus
|
| Purity |
> 88 % by SDS-PAGE.
|
| Bioactivity |
Specific Activity: 1204 pmol/min/μg. Assay Conditions: 25 μl kinase reaction is conducted in 40 mM Tris-HCl (pH 7.5), 10 mM MgCl 2 , 100 μM ATP, 200 μM of PI3K substrate and the PI3K enzyme for 15 minutes at 30°C. Conversion of ATP to ADP is detected.
|
| SwissProt/Accession |
P42336
|
| Gene |
PIK3CA
|
| Residue |
1 to 1068
|
| Sequence |
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELF KEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLK VIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEA VDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSP NNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKY ILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRD IDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAA RLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPH GLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSV SREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDF LWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLV RFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLK HLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQG FLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEII FKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEV VRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRE RVPFVLTQDFLIVISKGAQECTKTREFERFQ
|
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