Name |
Active human SIRT1 full length protein
|
Supplier |
Abcam
|
Catalog |
ab187228
|
Category |
Protein
|
Prices |
$745.00
|
Sizes |
50 µg
|
Applications |
SDS-PAGE
|
Species Reactivities |
Human
|
Nature |
Recombinant
|
Source |
E. coli
|
Tag/Conjugation |
His tag N-Terminus
|
Purity |
> 70 % by SDS-PAGE.
|
Bioactivity |
> 15 nmol/min/mg SIRT1 at 37 °C, 500 μM p53 K382 peptide (RHK-acetylK-LMFK), 1 mM NAD+.
|
SwissProt/Accession |
Q96EB6
|
Gene |
SIRT1
|
Residue |
1 to 747
|
Sequence |
MADEAALALQPGGSPSAAGADREAASSPAGEPLRKRPRRDGPGLERSPGE PGGAAPEREVPAAARGCPGAAAAALWREAEAEAAAAGGEQEAQATAAAGE GDNGPGLQGPSREPPLADNLYDEDDDDEGEEEEEAAAAAIGYRDNLLFGD EIITNGFHSCESDEEDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRT ILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLL QECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIE YFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTL EQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPA DEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVAL IPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKL CCNPVKLSEITEKPPRTQKELAYLSELPPTPLHVSEDSSSPERTSPPDSS VIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDL KNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLDGNQYLFLPPNRY IFHGAEVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYN GLEDEPDVPERAGGAGFGTDGDDQEAINEAISVKQEVTDMNYPSNKS
|
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