Active human TNF alpha protein fragment

• Supplier: Abcam
• Catalog: ab157349
• Category: Protein
• Prices: $352.00
• Sizes: 50 µg
• Applications: FA SDS-PAGE
• Species Reactivities: Human
• Nature: Recombinant
• Source: E. coli
• Tag/Conjugation: DDDDK tag N-Terminus
• Purity: >95% by SDS-PAGE .
• Bioactivity: Binds to Human and mouse TNF-R1 and less efficiently to TNF-R2. In the presence of cross-linking enhancer, TNF alpha shows a significantly higher affinity for TNF-R2 than for TNF-R1, mimicking the characteristics of membrane-bound TNF alpha. Exerts its biological activity in a concentration range of 0.1-1ng/ml (WEHI 164 cells). Specific Activity: ED 50 : 0.1ng/ml (WEHI 164 cells)
• Endotoxin: < 0.100 Eu/µg
• SwissProt/Accession: P01375
• Gene: TNF
• Residue: 85 to 223
• Sequence: SDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLI YSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEG AEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL