TrkA protein (Fc Chimera)
| Name | TrkA protein (Fc Chimera) |
|---|---|
| Supplier | Abcam |
| Catalog | ab83562 |
| Category | Protein |
| Applications | SDS-PAGE |
| Species Reactivities | Human |
| Nature | Recombinant |
| Source | HEK 293 cells |
| Purity | > 95 % by SDS-PAGE. |
| SwissProt/Accession | P04629 |
| Gene | NTRK1 |
| Residue | 33 to 405 |
| Sequence | Theoretical sequence: AAPCPDACCPHGSSGLRCTRDGALDSLHHLPGAENLTEL YIENQQH LQHLELRDLRGLGELRNLTIVKSGLRFVAPDAFHFTPRLSR LNLSF NALESLSWKTVQGLSLQELVLSGNPLHCSCALRWLQRWEEEGL GGV PEQKLQCHGQGPLAHMPNASCGVPTLKVQVPNASVDVGDDVLLRC Q VEGRGLEQAGWILTELEQSATVMKSGGLPSLGLTLANVTSDLNRKN VTCWAENDVGRAEVSVQVNVSFPASVQLHTAVEMHHWCIPFSVDGQ P APSLRWLFNGSVLNETSFIFTEFLEPAANETVRHGCLRLNQPTHV NNG NYTLLAANPFGQASASIMAAFMDNPFEFNPEDPIPVSFSPVDT NSTSE IPKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPK DTLMISR TPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREE QYNSTYRVV SVLTVLHQDWLNGKEYKCRVSNKALPAPIEKTISKAK GQPREPQVYTL PPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQ PENNYKTTPPVLD SDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEAL HNHYTQKSLSLSPGK |
| Supplier Page | Shop |
Product images
Lane 1 – MW markers; Lane 2 – ab83562; Lane 3 – ab83562 treated with PNGase F to remove potential N-linked glycans; 10 µg protein loaded per lane; Deep Purple™ stained. The drop in MW after treatment with PNGase F indicates presence of N-linked glycans.
Post-translational modifications result in protein heterogeneity. The densitometry scan demonstrates that ab83562 exists in multiple isoforms, which differ according to their level of post-translational modification. Expression of these isoforms is highly significant for cell biology, as they more closely resemble the native human proteins. The triangle indicates theoretical pI and MW of the protein.