Name |
Rat GM-CSF
|
Supplier |
ABBIOTEC
|
Catalog |
600374
|
Category |
Protein
|
Prices |
$250.00
|
Sizes |
20 µg
|
Species Reactivities |
Rat
|
Nature |
Recombinant
|
Source |
E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
|
Purity |
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
|
Bioactivity |
The activity is determined by the dose-dependant proliferation of the mouse FDC-P1 cell line and is typically less than 100 pg/mL. Specific activity: 1 x 10e7 units/mg
|
Gene |
Fgf2
|
Sequence |
MAPTRSPNPV TRPWKHVDAI KEALSLLNDM RALENEKNED VDIISNEFSI QRPTCVQTRL KLYKQGLRGN LTKLNGALTM IASHYQTNCP PTPETDCEIE VTTFEDFIKN LKGFLFDIPF DCWKPVQK
|
Description |
Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) is hematopoietic factor produced by entothelial cells, monocytes, fibroblasts and T cells in response to a number of inflammatory mediators. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages. Human and mouse GM-CSF show no cross-reactivity. Rat GM-CSF is produced in E.coli. Recombinant rat GM-CSF is a non-glycosylated protein, containing 128 amino acids, with a molecular weight of 14.6 kDa.
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