Fgf2

Gene Symbol	Fgf2
Entrez Gene	54250
Alt Symbol	Fgf-2, bFGF
Species	Rat
Gene Type	protein-coding
Description	fibroblast growth factor 2
Other Description	HBGF-2|basic fibroblast growth factor|heparin-binding growth factor 2
Swissprots	P13109
Accessions	AAC53225 EDM01301 EDM01302 EDM01303 EDM01304 P13109 M22427 AAA41210 X07285 CAA30265 NM_019305 NP_062178
Function	Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro (By similarity). {ECO:0000250}.
Subcellular Location	Secreted {ECO:0000250}. Nucleus {ECO:0000250}. Note=Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism. Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane (By similarity). Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57 (By similarity). {ECO:0000250}.
Tissue Specificity	Found in all tissues examined.
Top Pathways	Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Recombinant Rat FGF basic/FGF2 Protein - NBP2-35239 from Novus Biologicals Category Protein Prices $69.00, $169.00, $1,229.00 Sizes 10 µg, 50 µg, 1 mg Source E. coli Species Rat

FGF basic/FGF2 Recombinant Protein - P5037 from Novus Biologicals Category Protein Prices $449.00 Sizes 50 µg Species Rat

Recombinant Rat FGF basic/FGF2 Protein - NBP1-99874 from Novus Biologicals Category Protein Prices $195.00 Sizes 50 µg Source E. coli Species Rat

FGF basic/FGF2 Protein - NBP1-99781 from Novus Biologicals Category Protein Species Rat

FGF2 Recombinant Protein (Active) - GTX48259-PRO from GeneTex Category Protein Prices $299.00 Sizes 50 μg Source E. coli Species Rat

FGF2 recombinant protein - GTX65429 from GeneTex Category Protein Prices $199.00 Sizes 10 μg Source E. coli Species Rat

FGF2 recombinant protein - GTX65428 from GeneTex Category Protein Prices $249.00 Sizes 50 μg Source E. coli Species Rat

Recombinant Rat FGF basic - 3339-FB-025 from R&D Systems Category Protein Source E. coli-derived, Ala11-Ser154

Recombinant Rat FGF basic, CF - 3339-FB-025/CF from R&D Systems Category Protein Source E. coli-derived, Ala11-Ser154

FGF 2 Protein (OPPA01621) - OPPA01621 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 10 µg Source E. Coli

FGF2 protein - 30R-2339 from Fitzgerald Category Protein Prices $125.00, $275.00 Sizes 10 µg, 50 µg Source E.coli Species Rat

FGF basic / FGF2 - AR09493PU-N from Acris Antibodies Category Protein Prices $235.00 Sizes 50 µg Source E. coli Species Rat

FGF basic / FGF2 - AR09493PU-S from Acris Antibodies Category Protein Prices $135.00 Sizes 10 µg Source E. coli Species Rat

FGF basic / FGF2 - AR31055PU-L from Acris Antibodies Category Protein Prices $235.00 Sizes 50 µg Source E. coli Species Rat

FGF basic / FGF2 - AR31055PU-N from Acris Antibodies Category Protein Prices $135.00 Sizes 10 µg Source E. coli Species Rat

FGF basic / FGF2 - P5037 from Acris Antibodies Category Protein Prices $430.00 Sizes 50 µg Species Rat

Fibroblast Growth Factor-basic, Rat Recombinant - 228-10453-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Rat

Recombinant Rat bFGF / FGF basic / FGF2 - 228-10453-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Rat

Recombinant Rat bFGF / FGF basic / FGF2 - 228-10453-3 from RayBiotech Category Protein Prices $1,530.00 Sizes 3 µg Source Escherichia Coli. Species Rat

FGF Basic Recombinant Protein - 40-480 from ProSci Category Protein Prices $150.00, $250.00 Sizes 10 µg, 50 µg Source E. coli Species Rat

FGF 2 Rat - CYPS-615 from NeoScientific Category Protein Prices $65.00, $169.00, $1,638.00 Sizes 10 µg, 50 µg, 1 mg Source Escherichia Coli. Species Rat

Rat GM-CSF - 600374 from ABBIOTEC Category Protein Prices $250.00 Sizes 20 µg Source E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug. Species Rat

Recombinant Rat FGF2 Protein - BP000183-CYT-608 from Syd Labs Category Protein Prices $160.00, $1,260.00 Sizes 50 µg, 1 mg Source E. coli-derived. Species Rat

GMP Recombinant Rat bFGF - Fgf2-208R from Creative Biomart Category Protein Source E.coli Species Rat

FGF 2 Rat - BCA-204 from Reagent Proteins Category Protein Prices $348.00, $1,477.00 Sizes 50.00 µg, 1 mg Source E.coli Species Rat

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