Human IHH

Name Human IHH
Supplier ABBIOTEC
Catalog 600393
Category Protein
Prices $250.00
Sizes 25 µg
Species Reactivities Human
Source E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
Purity Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Bioactivity The activity is determined by the dose-dependent induction of alkaline phosphatase activity of CCL-226 cells and is typically less than 10 ug/mL. Specific activity: 1 x 10e2 units/mg
Gene IHH
Sequence MIIGPGRVVG SRRRPPRKLV PLAYKQFSPN VPEKTLGASG RYEGKIARSS ERFKELTPNY NPDIIFKDEE NTGADRLMTQ RCKDRLNSLA ISVMNQWPGV KLRVTEGWDE DGHHSEESLH YEGRAVDITT SDRDRNKYGL LARLAVEAGF DWVYYESKAH VHCSVKSEHS AAAKTGG
Description Indian Hedgehog (IHH) is a developmental factor found in the gut, cartilage and bones of an embryo. IHH acts through the patched (PTC) receptor and induces transcriptional changes important for bone development and include the up regulation of parathyroid hormone-related protein (PTHRP). Human IHH is produced in E. coli as a non-glycosylated protein, containing 177 amino acids, with a molecular weight of 20 kDa.
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