Gene Symbol | IHH |
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Entrez Gene | 3549 |
Alt Symbol | BDA1, HHG2 |
Species | Human |
Gene Type | protein-coding |
Description | indian hedgehog |
Other Description | HHG-2|Indian hedgehog homolog|indian hedgehog protein |
Swissprots | Q8N4B9 Q14623 O43322 B9EGM5 |
Accessions | AAX88920 BAA33523 BAA36285 CAJ18810 CAM31803 EAW70675 Q14623 AI802733 BC034757 AAH34757 BC136587 AAI36588 BC136588 AAI36589 L38517 AAA62178 NM_002181 NP_002172 |
Function | Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:21537345}. |
Tissue Specificity | Expressed in embryonic lung, and in adult kidney and liver. |
Top Pathways | Hedgehog signaling pathway |
Mouse Ihh peptide - ab39633 from Abcam
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IHH Antibody Blocking Peptide - LS-E3726 from LifeSpan Bioscience
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Recombinant Human Indian Hedgehog C28II Protein - NBP2-35012 from Novus Biologicals
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IHH-Antibody-N-term-Blocking-Peptide - BP14935a from Abgent, a WuXi AppTec company
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Recombinant Human Indian hedgehog protein(IHH) (OPCA00290) - OPCA00290 from Aviva Systems Biology
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Human IHH protein - orb244821 from Biorbyt
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Human IHH protein - orb168559 from Biorbyt
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IHH Blocking Peptide - 33R-1064 from Fitzgerald
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Human IHH Protein - abx067030 from Abbexa
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Hedgehog Homolog, Indian (IHH), Human - 20-8686 from ARP American Research Products
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IHH fusion protein - ag4046 from Proteintech Group
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IHH Human - CYPS-202 from NeoScientific
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Human IHH - 600393 from ABBIOTEC
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Recombinant Human IHH - IHH-656H from Creative Biomart
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Recombinant Hedgehog Homolog, Indian (IHH) - RPD116Hu01 from Uscn Life Science Inc.
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Recombinant Hedgehog Homolog, Indian (IHH) - RPD116Mu01 from Uscn Life Science Inc.
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Recombinant Hedgehog Homolog, Indian (IHH) - RPD116Mu02 from Uscn Life Science Inc.
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Recombinant Hedgehog Homolog, Indian (IHH) - RPD116Ra01 from Uscn Life Science Inc.
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IHH, Human - Z03277-50 from GenScript
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IHH, Human - Z03277-10 from GenScript
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IHH, Human - Z03277-1 from GenScript
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Recombinant Hedgehog Homolog, Indian (IHH) - RPD116Hu01 from Cloud-clone
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Recombinant Human Indian hedgehog protein(IHH) - CSB-YP622779HU CSB-BP622779HU CSB-MP622779HU from Cusabio
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Recombinant Human Indian hedgehog protein(IHH) - CSB-EP622779HU from Cusabio
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Recombinant Indian hedgehog protein(ihh) - CSB-YP011569DIK CSB-EP011569DIK CSB-BP011569DIK CSB-MP011569DIK from Cusabio
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