| Name | SMURF1 Peptide |
|---|---|
| Supplier | ABBIOTEC |
| Catalog | 350487 |
| Category | Peptide |
| Prices | $50.00 |
| Sizes | 100 µg |
| Purity | Purity > 80% by HPLC |
| Gene | SMURF1 |
| Sequence | The synthetic peptide used to raise the antibody Cat. No. 200125 is selected from a sequence within the center region of human SMURF1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
| Description | SMURF1 is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and directly transfers the ubiquitin to targeted substrates. SMURF1 interacts with receptor-regulated SMADs specific for the BMP pathway, SMAD1 and SMAD5, in order to trigger their ubiquitination and degradation. |
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