Name | GTP-CH-1 Peptide |
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Supplier | ABBIOTEC |
Catalog | 350575 |
Category | Peptide |
Prices | $80.00 |
Sizes | 100 µg |
Purity | Purity > 80% by HPLC |
Gene | GCH1 |
Sequence | The synthetic peptide used to raise the antibody Cat. No. 250680 is selected from a sequence within the N-term region of human GTP-CH-1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
Description | GCH-1 catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. The final product (BH4) is an essential co-factor for three aromatic amino acid monooXygenases (F,Y, and W). Isoform GCH-1 is the functional enzyme. |
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