| Name | Exostosin-1 Peptide |
|---|---|
| Supplier | ABBIOTEC |
| Catalog | 350499 |
| Category | Peptide |
| Prices | $50.00 |
| Sizes | 100 µg |
| Purity | Purity > 80% by HPLC |
| Gene | EXT1 |
| Sequence | The synthetic peptide used to raise the antibody Cat. No. 200137 is selected from a sequence within the C-term region of human Exostosin-1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
| Description | Exostosin-1 (EXT1) is a glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. EXT1 is a tumor suppressor. Defects in EXT1 are the cause of multiple exostoses disorders, i.e. skeletal deformities and bone tumors. |
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