Name | Dnmt3b Peptide |
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Supplier | ABBIOTEC |
Catalog | 350465 |
Category | Peptide |
Prices | $50.00 |
Sizes | 100 µg |
Purity | Purity > 80% by HPLC |
Gene | DNMT3B |
Sequence | The synthetic peptide used to raise the antibody Cat. No. 200103 is selected from a sequence within the N-term region of human Dnmt3b. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
Description | Dnmt3B is required for genome wide de novo methylation and is essential for development. Defects in Dnmt3B are a cause of immunodeficiency-centromeric instability-facial abnomalies syndrome (ICF), characterized biochemically by hypomethylation of CpG sites in heterochromatin. |
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