Name | AEBP1 Peptide |
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Supplier | ABBIOTEC |
Catalog | 350560 |
Category | Peptide |
Prices | $50.00 |
Sizes | 100 µg |
Purity | Purity > 80% by HPLC |
Gene | AEBP1 |
Sequence | The synthetic peptide used to raise the antibody Cat. No. 200198 is selected from a sequence within the N-term region of AEBP1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
Description | Adipocyte enhancer-binding protein 1 (AEBP1) up-regulates MAP-kinase activity leading to enhanced proliferation and reduced differentiation of the adipocyte. AEBP1 also up-regulates NF-kappa-B activity in macrophages via phosphorylation and subsequent degradation of I-kappa-B-alpha. This leads to enhanced macrophage inflammatory responsiveness. It can also act as a transcriptional repressor. |
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