Gene Symbol | AEBP1 |
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Entrez Gene | 165 |
Alt Symbol | ACLP |
Species | Human |
Gene Type | protein-coding |
Description | AE binding protein 1 |
Other Description | adipocyte enhancer-binding protein 1|aortic carboxypeptidase-like protein |
Swissprots | Q59ER7 Q14113 Q7KZ79 Q6ZSC7 Q8IUX7 |
Accessions | EAL23768 EAW61119 Q8IUX7 AB209744 BAD92981 AF053944 AAC25585 AK090931 BAG52248 AK127541 BAC87026 AK296001 BAG58775 BC038588 AAH38588 BM672693 D86479 BAA13094 DB213495 XM_011515162 XP_011513464 NM_001129 NP_001120 |
Function | May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor. {ECO:0000250}. |
Subcellular Location | Isoform 1: Secreted {ECO:0000250}. |
Tissue Specificity | Expressed in osteoblast and visceral fat. {ECO:0000269|PubMed:8920928}. |
Human AEBP1 protein fragment - ab157867 from Abcam
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ACLP / AEBP1 Antibody Blocking Peptide - LS-E42 from LifeSpan Bioscience
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ACLP / AEBP1 Antibody Blocking Peptide - LS-E11040 from LifeSpan Bioscience
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Recombinant Human AE Binding Protein 1/ACLP Protein - H00000165-Q01 from Novus Biologicals
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AEBP1-Antibody-Center-Blocking-peptide - BP10098c from Abgent, a WuXi AppTec company
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AEBP1 / ACLP - H00000165-Q01-10 from Acris Antibodies
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AEBP1 / ACLP - H00000165-Q01-25 from Acris Antibodies
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AEBP1 Peptide - 350560 from ABBIOTEC
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Recombinant AE Binding Protein 1 (AEBP1) - RPJ668Hu01 from Uscn Life Science Inc.
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Recombinant AE Binding Protein 1 (AEBP1) - RPJ668Hu01 from Cloud-clone
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Recombinant Human Adipocyte enhancer-binding protein 1(AEBP1) ,partial - CSB-YP814205HU CSB-EP814205HU CSB-BP814205HU CSB-MP814205HU from Cusabio
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Adipocyte enhancer-binding protein 1(AEBP1) ,partial - MBS1444515 from MyBioSource
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AE Binding Protein 1/ACLP Recombinant Protein Antigen - NBP2-49432PEP from Novus Biologicals
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AE Binding Protein 1/ACLP Recombinant Protein Antigen - NBP2-49398PEP from Novus Biologicals
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AEBP1 Peptide, Human - M34GP00343H from Creative Peptides
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AEBP1 protein - orb86081 from Biorbyt
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