Name | ABCB6 Peptide |
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Supplier | ABBIOTEC |
Catalog | 300116 |
Category | Peptide |
Prices | $80.00 |
Sizes | 100 µg |
Purity | Purity > 80% by HPLC |
Gene | ABCB6 |
Sequence | The synthetic peptide used to raise the antibody Cat. No. 250549 is selected from a sequence within the N-term region of human ABCB6. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
Description | ATP-binding cassette sub-family B member 6, mitochondrial (ABCB6) binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. ABCB6 plays a crucial role in heme synthesis. Depletion of ABCB6 by RNAi abrogates heme biosynthesis. Overexpression enhances porphyrin biosynthesis. |
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