ABCB6

Gene Symbol	ABCB6
Entrez Gene	10058
Alt Symbol	ABC, ABC14, DUH3, LAN, MCOPCB7, MTABC3, PRP, umat
Species	Human
Gene Type	protein-coding
Description	ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
Other Description	ATP-binding cassette half-transporter|ATP-binding cassette sub-family B member 6, mitochondrial|P-glycoprotein-related protein|mitochondrial ABC transporter 3|mt-ABC transporter 3|ubiquitously-expressed mammalian ABC half transporter
Swissprots	Q9HAQ7 Q59GQ5 Q6ZME6 Q9HAQ6 Q49A66 O75542 Q96ME8 Q9NP58
Accessions	AAG33618 BAA96733 BAN91499 BAN91500 BAN91501 BAN91502 BAN91503 BAN91504 EAW70694 EAW70695 EAW70696 EAW70697 EAW70698 EAW70699 EAW70700 EAW70701 EAW70702 EAW70703 EAW70704 EAW70705 Q9NP58 AF070598 AAC28653 AF076775 AAF75107 AF308472 AAG33617 AJ289233 CAB95766 AK026067 AK057026 BAB71347 AK172812 BAD18782 AK303230 BAG64317 AL560811 AW664349 BC000559 AAH00559 BC043423 AAH43423 DQ891876 ABM82802 DQ895063 ABM85989 U66673 NM_005689 NP_005680
Function	Binds heme and porphyrins and functions in their ATP- dependent uptake into the mitochondria. Plays a crucial role in heme synthesis. {ECO:0000269|PubMed:10837493, ECO:0000269|PubMed:17006453}.
Subcellular Location	Cell membrane. Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum. Golgi apparatus. Endosome {ECO:0000250}. Note=localized to the endosome- like compartement and dendrite tips.
Tissue Specificity	Widely expressed. High expression is detected in the retinal epithelium. {ECO:0000269|PubMed:10837493, ECO:0000269|PubMed:22226084}.
Top Pathways	ABC transporters

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ABCB6 protein (His tag) - ab127452 from Abcam Category Protein Prices $364.00 Sizes 50 µg Source E. coli Species Human

ABCB6 Antibody Blocking Peptide - LS-E15548 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ABCB6 Partial Recombinant Protein - H00010058-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ABCB6 Blocking Peptide - 33R-9841 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ABCB6 - H00010058-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ABCB6 - H00010058-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ABCB6 fusion protein - ag1541 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ABCB6 fusion protein - Ag7045 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

ABCB6 fusion protein - Ag6982 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

ABCB6 fusion protein - ag0461 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ABCB6 Peptide - 300116 from ABBIOTEC Category Peptide Prices $80.00 Sizes 100 µg

Recombinant ATP Binding Cassette Transporter B6 (ABCB6) - RPD636Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

ABCB6 Recombinant Protein Antigen - NBP1-91642PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ABCB6-Antibody-C-term-Blocking-Peptide - BP6113a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ABCB6 Peptide, Human - M34GP00045H from Creative Peptides Category Peptide Source Synthetic. Species Human

ABCB6 Recombinant Protein (OPCD00419) - OPCD00419 from Aviva Systems Biology Category Protein Source E.coli Species Human

ABCB6 Recombinant Protein Antigen - NBP2-58327PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Recombinant Human ABCB6 Protein, GST-Tagged - ABCB6-040H from Creative Biomart Category Protein Source Wheat Germ Species Human

Recombinant Human ABCB6 protein, His & T7-tagged - ABCB6-8125H from Creative Biomart Category Protein Source E. coli Species Human

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