Name | RGS17, 1-210aa, Recombinant Protein |
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Supplier | Genway Biotech |
Catalog | GWB-P0838F |
Category | Protein |
Prices | $300.00, $900.00 |
Sizes | 100 μg, 500 μg |
Applications | SDS-PAGE |
Species Reactivities | Human |
Nature | Recombinant |
Source | E.coli |
Tag/Conjugation | His-tag |
Purity | Greater than 90% by SDS - PAGE |
Gene | RGS17 |
Sequence | MGSSHHHHHH SSGLVPRGSH MRKRQQSQNE GTPAVSQAPG NQRPNNTCCF CWCCCCSCSC LTVRNEERGE NAGRPTHTTK MESIQVLEEC QNPTAEEVLS WSQNFDKMMK APAGRNLFRE FLRTEYSEEN LLFWLACEDL KKEQNKKVIE EKARMIYEDY ISILSPKEVS LDSRVREVIN RNLLDPNPHM YEDAQLQIYT LMHRDSFPRF LNSQIYKSFV ESTAGSSSES |
Description | RGS17, also known as regulator of G-protein signaling 17, attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal |
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