Gene Symbol | RGS17 |
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Entrez Gene | 26575 |
Alt Symbol | RGS-17, RGSZ2, hRGS17 |
Species | Human |
Gene Type | protein-coding |
Description | regulator of G-protein signaling 17 |
Other Description | - |
Swissprots | Q8TD61 Q5TF49 Q9UJS8 Q9UGC6 |
Accessions | CAK32368 EAW47711 Q9UGC6 AA902430 AF202257 AAF08978 AF493938 AAM12652 BC013117 AAH13117 BT006997 AAP35643 CK902282 XM_011535752 XP_011534054 XM_011535753 XP_011534055 XM_011535754 XP_011534056 NM_012419 NP_036551 |
Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G- protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Lipid-anchor. Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm/cell membrane and the nucleus. Anchored to the membrane through palmitoylation (By similarity). {ECO:0000250}. |
Tissue Specificity | Predominantly expressed in the cerebellum. Also expressed in the cortex and medulla. Weakly expressed in a number of peripheral tissues notably spleen, lung and leukocytes. {ECO:0000269|PubMed:15096504}. |
Human RGS17 / RGSZ2 full length protein - ab132129 from Abcam
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Human RGS17 / RGSZ2 protein fragment - ab162013 from Abcam
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RGS17 / RGSZ2 peptide - ab45469 from Abcam
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RGS17 / RGSZ2 Antibody Blocking Peptide - LS-E25724 from LifeSpan Bioscience
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RGS17 Partial Recombinant Protein - H00026575-Q01 from Novus Biologicals
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RGS17 Recombinant Protein - H00026575-P01 from Novus Biologicals
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Recombinant Human RGS17 Protein - NBP1-72443 from Novus Biologicals
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RGS17 blocking peptide - GTX14815-PEP from GeneTex
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Human RGS17 protein - orb169185 from Biorbyt
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RGS17 protein (His tag) - 80R-1956 from Fitzgerald
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RGS17 Blocking Peptide - abx064248 from Abbexa
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RGS17 / RGSZ2 Peptide - AC21-0553-P from Abcore
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RGS17 (1-210, His-tag) - AR39142PU-L from Acris Antibodies
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RGS17 (1-210, His-tag) - AR39142PU-N from Acris Antibodies
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RGS17 - H00026575-P01-02 from Acris Antibodies
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RGS17 - H00026575-Q01-10 from Acris Antibodies
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RGS17 - H00026575-Q01-25 from Acris Antibodies
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RGS17, 1-210aa, Human, His tag, E.coli - 01-1796-17 from ARP American Research Products
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RGS17 Peptide - 46-289P from ProSci
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RGS17 fusion protein - ag3399 from Proteintech Group
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Recombinant Human Regulator of G-Protein Signaling 17 - BP002414-PRO-924 from Syd Labs
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RGS17, 1-210aa, Recombinant Protein - GWB-P0838F from Genway Biotech
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Recombinant Human RGS17, His-tagged - RGS17-3639H from Creative Biomart
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RGS17 1-210aa - CMB-1033 from Reagent Proteins
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RGS17 Blocking Peptide - CBP3054 from Cohesion Biosciences
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