Recombinant Human Protein Phosphatase Inhibitor-1

• Supplier: Genway Biotech
• Catalog: GWB-49D423
• Category: Protein
• Prices: $75.00, $165.00, $4,035.00
• Sizes: 5 μg, 20 μg, 1000 μg
• Species Reactivities: Human
• Nature: Recombinant
• Purity: Greater than 90.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• SwissProt/Accession: Q13522
• Gene: PPP1R1A
• Sequence: M E QDNSPRKIQFTVPLL E PHLDP E A A E QIRRRRPTP A TLVLTSDQSSP E ID E DRIPNPHLKSTL A MSPRQRKKMTRITPTMK E LQMMV E HHLGQQQQG E E P E G A A E STGTQ E SRPPGIPDT E V E SRLGTSGT A KKT A E CIPKTH E RGSK E PSTK E PSTHIPPLDSKG A NSVL E HHHHHH Introduction: PPP1R1A is an inhibitor of protein-phosphatase 1. IPP-1 protein plays important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP elevate IPP-1 activity. PPP1R1A activation caused cAMP to control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium, IPP-1 is inactivated by calcineurin (PP2B). Multiple domains in IPP-1 target cellular PP1 complexes. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation.Description: PPP1R1A Human Recombinant fused with His tag at C-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 179 amino acids and having a molecular mass of 20 kDa.The PPP1R1A is purified by proprietary chromatographic
• Description: Recombinant Human Protein Phosphatase Inhibitor-1