Gene Symbol | PPP1R1A |
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Entrez Gene | 5502 |
Alt Symbol | I1, IPP1 |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
Other Description | I-1|IPP-1|inhibitor-1|protein phosphatase 1 regulatory subunit 1A|protein phosphatase inhibitor 1|protein phosphatase inhibitor-1 |
Swissprots | Q6IB01 Q13522 Q8WWV2 Q8TBJ2 |
Accessions | EAW96792 Q13522 AK123969 BAC85737 AY063766 AAL48321 BC022470 AAH22470 BM876308 BP211831 CR457003 CAG33284 U48707 AAB02402 XM_005268995 XP_005269052 XM_006719471 XP_006719534 XM_011538521 XP_011536823 XM_011538522 XP_011536824 NM_006741 NP_006732 |
Function | Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. |
Top Pathways | Long-term potentiation, Adrenergic signaling in cardiomyocytes |
Human Protein phosphatase inhibitor 1 full length protein - ab78756 from Abcam
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Human Protein phosphatase inhibitor 1 full length protein - ab117672 from Abcam
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PPP1R1A / IPP1 Antibody Blocking Peptide - LS-E15568 from LifeSpan Bioscience
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Recombinant Human Protein Phosphatase inhibitor 1 Protein - H00005502-P01 from Novus Biologicals
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PPP1R1A Protein (OPPA01682) - OPPA01682 from Aviva Systems Biology
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Human IPP1 protein - orb49617 from Biorbyt
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Human PPP1R1A protein - orb90241 from Biorbyt
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PPP1R1A (1-171, His-tag) - AR09053PU-L from Acris Antibodies
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PPP1R1A (1-171, His-tag) - AR09053PU-N from Acris Antibodies
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PPP1R1A - H00005502-P01-02 from Acris Antibodies
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Protein Phosphatase Inhibitor-1, Human Recombinant - 228-11297-1 from RayBiotech
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Recombinant Human PPP1R1A - 228-11297-2 from RayBiotech
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Recombinant Human PPP1R1A - 228-11297-3 from RayBiotech
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IPP-1, 1-171aa, Human, His-tagged, Recombinant, E.coli - 01-2289 from ARP American Research Products
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Protein Phosphatase 1 Regulatory Subunit 1A, PPP1R1A, Human, Recombinant - 19-C163 from ARP American Research Products
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PPP1R1A fusion protein - Ag3128 from Proteintech Group
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IPP-1, 1-171aa, Recombinant Protein - GWB-P0129L from Genway Biotech
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Recombinant Human Protein Phosphatase Inhibitor-1 - GWB-49D423 from Genway Biotech
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Recombinant Human Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1A, His-tagged - PPP1R1A-341H from Creative Biomart
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Recombinant Human PPP1R1A, GST-tagged - PPP1R1A-2049H from Creative Biomart
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Recombinant Human PPP1R1A, GST-tagged - PPP1R1A-1907H from Creative Biomart
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IPP-1 1-171aa - IBA-181 from Reagent Proteins
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IPP-1 - PAT-80142-1 from Nordic BioSite
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IPP-1 - PAT-80142-2 from Nordic BioSite
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IPP1 Blocking Peptide - CBP3000 from Cohesion Biosciences
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