Recombinant Human Calcium and Integrin Binding 1

Name Recombinant Human Calcium and Integrin Binding 1
Supplier Genway Biotech
Catalog GWB-8FF9E9
Category Protein
Prices $75.00, $165.00, $3,230.00
Sizes 5 μg, 25 μg, 1000 μg
Species Reactivities Human
Nature Recombinant
Purity Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
SwissProt/Accession Q99828
Gene CIB1
Sequence MGSSHHHHHHSSGLVPRGSHMGGSGSRLSK E LL A E YQDLTFLTKQ E ILL A HRRFC E LLPQ E QRTV E SSLR A QVPF E QILSLP E LK A NPFK E RICRVFSTSP A KDSLSF E DFLDLLSVFSDT A TPDIKSHY A FRIFDFDDDGTLNR E DLSRLVNCLTG E G E DTRLS A S E MKQLIDNIL E E SDIDRDGTINLS E FQHVISRSPDF A SSFKIVL. Introduction: CIB1 (Calcium and integrin binding 1) is regulatory protein with 50% homology to calmodulin and calcineurin B, that encodes a member of the calcium-binding protein family. CIB1 interacts with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. Also CIB1 is widely expressed and binds to a number of effectors, such as integrin ?IIb, PAK1, and polo-like kinases, in different tissues.Description: CIB1 Human Recombinant is a single, non-glycosylated polypeptide chain containing 211 amino acids and having a molecular mass of 23 kDa. CIB1 was overexpressed in E. coli as a soluble His-tag fusion protein, and it was purified by conventional column chromatographic techniques
Description Recombinant Human Calcium and Integrin Binding 1
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