| Name | PKA-RII alpha |
|---|---|
| Supplier | Genway Biotech |
| Catalog | GWB-3B9281 |
| Category | Protein |
| Prices | $75.00, $165.00, $4,155.00 |
| Sizes | 1 μg, 5 μg, 100 μg |
| Nature | Recombinant |
| Purity | Greater than 95% as determined by SDS-PAGE. |
| Bioactivity | PKA regulatory subunit alpha specifically inhibits PKA catalytic subunit (Ki about 0.7nM). The binding is not dependent on the presence of ATPMg, however, the regulatory subunit will be phosphorylated at the binding site by PKA C alpha upon binding. Activity can be restored by adding the second messenger cAMP (Kact about 100nM). Subcellular localisation is regulated via interaction of PKA RII with so-called A-kinase anchoring proteins (AKAPs). |
| SwissProt/Accession | P13861 |
| Gene | PRKAR2A |
| Description | Recombinant c-AMP dependant Protein Kinase A regulatory subunit 2 alpha |
| Supplier Page | Shop |