PRKAR2A

Gene Symbol PRKAR2A
Entrez Gene 5576
Alt Symbol PKR2, PRKAR2
Species Human
Gene Type protein-coding
Description protein kinase, cAMP-dependent, regulatory, type II, alpha
Other Description cAMP-dependent protein kinase regulatory subunit RII alpha|cAMP-dependent protein kinase type II-alpha regulatory subunit|protein kinase A, RII-alpha subunit
Swissprots Q16823 Q9BUB1 P13861
Accessions CAA67817 EAW64925 EAW64926 EAW64927 EAW64928 P13861 AK023535 AK026351 AK293042 BAF85731 BC002763 AAH02763 BT007225 AAP35889 CF994284 X14968 CAA33094 XM_005265313 XP_005265370 XM_005265314 XP_005265371 XM_005265315 XP_005265372 XM_011533942 XP_011532244 XM_011533943 XP_011532245 XR_427280 XR_940469 NM_004157 NP_004148
Function Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:21423175}. Cell membrane {ECO:0000269|PubMed:21423175}. Note=Colocalizes with PJA2 in the cytoplasm and the cell membrane.
Tissue Specificity Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
Top Pathways Apoptosis, Insulin signaling pathway

Human PKA R2 full length protein - ab132177 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab132177 stained with Coomassie Blue.

Human PKA R2 full length protein - ab202621 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE analysis of ab202621 (3 µg).

Human PKA R2 protein fragment - ab159196 from Abcam

Category Protein
Source Wheat germ
Species Human
ab159196 on a 12.5% SDS-PAGE stained with Coomassie Blue.

PKA R2 peptide - ab41297 from Abcam

Category Peptide

PRKAR2A Antibody Blocking Peptide - LS-E25173 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PKA R2 Partial Recombinant Protein - H00005576-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

PKA R2 Recombinant Protein - H00005576-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

PKA R2 Peptide - P2149 from Novus Biologicals

Category Peptide
Species Human

PRKAR2A Blocking Peptide - 33R-2001 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

PRKAR2A protein (His tag) - 80R-4182 from Fitzgerald

Category Protein
Prices $275.00
Sizes 100 µg
Source E.coli

PRKAR2A (1-404, His-tag) - AR51870PU-N from Acris Antibodies

Category Protein
Prices $790.00
Sizes 500 µg
Source E. coli
Species Human
PRKAR2A

PRKAR2A (1-404, His-tag) - AR51870PU-S from Acris Antibodies

Category Protein
Prices $340.00
Sizes 100 µg
Source E. coli
Species Human
PRKAR2A

PRKAR2A - H00005576-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

PRKAR2A - H00005576-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

PRKAR2A - H00005576-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

PRKAR2A - H00005576-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

PRKAR2A fusion protein - ag0203 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

PKA-RII alpha - GWB-3B9281 from Genway Biotech

Category Protein
Prices $75.00, $165.00, $4,155.00
Sizes 1 μg, 5 μg, 100 μg

PKACa2-RIIa2 - GWB-309567 from Genway Biotech

Category Protein
Prices $75.00, $165.00, $4,155.00
Sizes 1 μg, 5 μg, 100 μg

PKA IIα reg (P68) Peptide - BS1929P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl

Recombinant Human cAMP-dependent protein kinase type II-alpha regulatory subunit(PRKAR2A) - CSB-YP018697HU CSB-EP018697HU CSB-BP018697HU CSB-MP018697HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

PRKAR2A, 1-404aa, Human, His tag, E.coli - ATGP3050 from ATGen

Category Protein
Prices $80.00, $240.00, $720.00
Sizes 20 µg, 100 µg, 500 µg
Species Human
SDSPAGE

PRKAR2A - TP320376 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
PRKAR2A

cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A), Recombinant Protein - MBS718242 from MyBioSource

Category Protein
Prices $1,175.00, $1,175.00, $1,395.00, $1,395.00, $1,885.00, $1,885.00, $2,350.00, $2,350.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

PRKAR2A, Recombinant Protein - MBS205901 from MyBioSource

Category Protein
Prices $310.00, $720.00
Sizes 100 µg, 500 µg
Source E Coli
Species Human
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