| Name | Recombinant Human LGR5, Fc Chimera |
|---|---|
| Supplier | Creative Biomart |
| Catalog | LGR5-1037H |
| Category | Protein |
| Species Reactivities | Human |
| Nature | Recombinant |
| Source | CHO Cells |
| Tag/Conjugation | Fc |
| Purity | >90%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
| Bioactivity | Measured by its binding ability in a functional ELISA.When Recombinant Human R-Spondin 3 (Catalog # 3500-RS) is coated at 0.5 μg/mL, Recombinant Human Lgr5/GPR49 Fc Chimera binds with an apparent Kd <0.1 nM. Measured by its ability to inhibit Topflash reporter activity in HEK293T human embryonic kidney cells.The ED50 for this effect is typically 1.5-7.5 μg/mL in the presence of 20 ng/mL Recombinant Human R-Spondin 2 (Catalog # 3266-RS) and 5 ng/mL Recombinant Mouse Wnt-3a (Catalog # 1324-WN). |
| SwissProt/Accession | O75473 |
| Gene | LGR5 |
| Description | Recombinant Human LGR5 (Accession # O75473), fused with , was produced in Chinese Hamster Ovary cell line, CHO-derived. |
| Supplier Page | Shop |